Paper · 2020 · Pharmacognosy Journal

Potential Test of Nephropathy Sonchus arvensis L. Leaves on Male Rats (Rattus norvegicus) Diabetes Mellitus

Joni Tandi; I Nyoman Edi Sutrisna; Mentari Pratiwi; et al.

4
claims
7
verbatim quotes
17
citations
1
research areas
✓
Open access · cc-by

Abstract

This study aims to determine the type of secondary metabolites compounds of the ethanol Sonchus arvensis L leaves extract, the effect of ethanol Sonchus arvensis L leaves extracts the levels of blood glucose and a histopathology picture male white rat induced by streptozotocin. This study used 30 males white rats which were divided into 6 groups, namely the control of normal, negative control, positive control, doses of 200, 300 and 400 mg/kg BW. Results of the study showed that the ethanol Sonchus arvensis L. leaves extracts contained compounds of alkaloids, flavonoids, phenols, saponins and tannins. Sonchus arvensis L ethanol extract at a dose of 300 mg/kg BW is an effective dose in reducing blood glucose levels with an average value of decreasing blood glucose levels 101.6 mg / dL and has an effect on the regeneration of renal tubular cells with an effective dose is 300 mg / kg body weight with an average damage value of 0.28.

Abstract from the paper’s OpenAlex record; open copy licensed cc-by. Read at the source ↗

The text the model read, with the source record’s inline markup (italics, sub- and superscripts) rendered and its character entities decoded; quote offsets refer to the raw text.

Claims 4

Observationobservedoriginal resultmeasured

Claim · model-written summary

The ethanol leaf extract contained alkaloids, flavonoids and phenols.

Taxon
Sonchus arvensis L.Sonchus arvensise0
Organ / stage
leavese0
Outcome
alkaloids, flavonoids, phenolse0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Sonchus arvensis
Sonchus arvensis · TaxonDonald Hobern from Copenhagen, Denmark · CC BY 2.0 · Wikimedia Commons ↗

Verbatim

e0

“Results of the study showed that the ethanol Sonchus arvensis L. leaves extracts contained compounds of alkaloids, flavonoids, phenols, saponins and tannins.”

✓ located verbatim in the source · abstract, characters 451–608 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

The ethanol leaf extract contained saponins and tannins.

Taxon
Sonchus arvensis L.Sonchus arvensise0
Organ / stage
leavese0
Outcome
saponins and tanninse0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Sonchus arvensis
Sonchus arvensis · TaxonDonald Hobern from Copenhagen, Denmark · CC BY 2.0 · Wikimedia Commons ↗

Verbatim

e0

“Results of the study showed that the ethanol Sonchus arvensis L. leaves extracts contained compounds of alkaloids, flavonoids, phenols, saponins and tannins.”

✓ located verbatim in the source · abstract, characters 451–608 · show in text ↑
Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Sonchus ethanol extract at 300 mg/kg BW reduced rat blood glucose by an average 101.6 mg / dL.

Taxon
Rattus norvegicusRattus norvegicust0
Treatment
Sonchus arvensis L ethanol extract at a dose of 300 mg/kg BWe0
Outcome
blood glucose levelse0
Direction
reducinge0
Value
101.6 mg / dLe0

Not reportedComparator

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Rattus norvegicus
Rattus norvegicus · TaxonMichael Palmer · CC BY-SA 4.0 · Wikimedia Commons ↗

Verbatim

e0

“Sonchus arvensis L ethanol extract at a dose of 300 mg/kg BW is an effective dose in reducing blood glucose levels with an average value of decreasing blood glucose levels 101.6 mg / dL”

✓ located verbatim in the source · abstract, characters 609–794 · show in text ↑
t0

“Rattus norvegicus”

✓ located verbatim in the source · title, characters 71–88 · show in text ↑

schema checkedfield values found in the cited quotesPermalinkReport an issue

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

The extract affected rat renal tubular cell regeneration at an effective dose of 300 mg / kg body weight, with average damage 0.28.

Taxon
Rattus norvegicusRattus norvegicust0
Treatment
Sonchus arvensis L ethanol extracte1
Outcome
regeneration of renal tubular cellse0
Value
0.28e0
Qualifier
300 mg / kg body weighte0

Not reportedComparatorDirection

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Rattus norvegicus
Rattus norvegicus · TaxonMichael Palmer · CC BY-SA 4.0 · Wikimedia Commons ↗

Verbatim

e0

“has an effect on the regeneration of renal tubular cells with an effective dose is 300 mg / kg body weight with an average damage value of 0.28”

✓ located verbatim in the source · abstract, characters 799–942 · show in text ↑
e1

“Sonchus arvensis L ethanol extract”

✓ located verbatim in the source · abstract, characters 609–643 · show in text ↑
t0

“Rattus norvegicus”

✓ located verbatim in the source · title, characters 71–88 · show in text ↑

schema checkedfield values found in the cited quotesPermalinkReport an issue