Abstract
Excess Ni intake has harmful implications on human health, which include chronic bronchitis, reduced lung function, and cancer of lung and nasal sinuses. Like other toxic metals, higher Ni accumulation in grains leads to excess intake by humans when the contaminated grains are consumed as food. There is little information about the genetic factors that regulate Ni uptake in plants. To investigate genetic architecture of Ni uptake in leaf and translocation to grain, we performed a genome-wide association study with genotyping from 90 K array in a historical bread wheat diversity panel from Pakistan. We observed that Ni toxicity caused more than 50 % reductions in biological yield and grain yield, other agronomic traits were also partly or severely affected. Genetic association study helped identify 23 SNP-trait associations involved in Ni uptake in leaf and translocation to grains. These 23 SNPs covered 15 genomic loci at chromosomes 1A, 2D, 3B, 4A and 4B of wheat. The favorable alleles of these SNPs were randomly distributed in subpopulations indicating no selection pressure for this trait during breeding improvement. These regions had 283 low-confidence and 248 high-confidence protein coding genes. Among these, 156 were annotated using databases of wheat and closely related grass species. Since there is no previous report on genetic information of Ni uptake and translocation, these results provide sufficient grounds for further research of candidate genes and varietal development.
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Claims 7
Claim · model-written summary
Ni toxicity reduced biological yield by more than 50% in wheat.
- Taxon
- spring wheat
Triticum aestivumt0 - Treatment
- Ni toxicitye0
- Outcome
- biological yielde0
- Direction
- reductionse0
- Value
- more than 50 %e0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“spring wheat”
e0“Ni toxicity caused more than 50 % reductions in biological yield and grain yield”
Claim · model-written summary
Ni toxicity reduced grain yield by more than 50% in wheat.
- Taxon
- spring wheatTriticum aestivumt0
- Treatment
- Ni toxicitye0
- Outcome
- grain yielde0
- Direction
- reductionse0
- Value
- more than 50 %e0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“spring wheat”
e0“Ni toxicity caused more than 50 % reductions in biological yield and grain yield”
Claim · model-written summary
Ni toxicity partly or severely affected other agronomic traits in wheat.
- Taxon
- spring wheatTriticum aestivumt0
- Treatment
- Ni toxicitye1
- Outcome
- other agronomic traitse0
- Qualifier
- partly or severelye0
Not reportedComparatorDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“spring wheat”
e0“other agronomic traits were also partly or severely affected”
e1“Ni toxicity caused more than 50 % reductions in biological yield and grain yield”
Claim · model-written summary
The wheat association study identified 23 SNP-trait associations for Ni uptake in leaves and translocation to grains, covering 15 loci on five chromosomes.
- Taxon
- wheatTriticum aestivume0
- Outcome
- 23 SNP-trait associations involved in Ni uptake in leaf and translocation to grainse0
- Value
- 23 SNP-trait associationse0
- Qualifier
- 15 genomic loci at chromosomes 1A, 2D, 3B, 4A and 4Be0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“spring wheat”
e0“Genetic association study helped identify 23 SNP-trait associations involved in Ni uptake in leaf and translocation to grains. These 23 SNPs covered 15 genomic loci at chromosomes 1A, 2D, 3B, 4A and 4B of wheat.”
Claim · model-written summary
Favorable alleles were randomly distributed among wheat subpopulations.
- Outcome
- favorable alleles of these SNPs were randomly distributed in subpopulationse0
Not reportedTaxon
Verbatim
e0“The favorable alleles of these SNPs were randomly distributed in subpopulations”
Claim · model-written summary
The mapped wheat regions contained 283 low-confidence and 248 high-confidence protein coding genes.
Not reportedTaxon
Verbatim
e0“These regions had 283 low-confidence and 248 high-confidence protein coding genes.”
Claim · model-written summary
Of the genes in the wheat regions, 156 were annotated using wheat and related grass databases.
- Taxon
- wheatTriticum aestivume0
- Outcome
- annotatede0
- Value
- 156e0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Among these, 156 were annotated using databases of wheat and closely related grass species.”
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See all 20 papers →Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.