Abstract
Chromatographic purification of the alcoholic extract from the aerial parts of the Saudi plant Nuxia oppositifolia (Hochst.), Benth., resulted in five isolated phenolic compounds. Two flavones, hispidulin (1) and jaceosidin (2), and the phenylethanoid glycosides, verbascoside (3), isoverbascoside (4), and conandroside (5), were identified and their chemical structures were determined by spectroscopic analyses. The insecticidal activity of compounds 1 and 2, in addition to 11 compounds isolated in a previous research (6–16), was evaluated against the Yellow Fever mosquito, Aedes aegypti. Four compounds displayed adulticidal activity with LD50 values of 2–2.3 μg/mosquito. Free radical scavenging properties of the plant extracts and compounds (1–5) were evaluated by measuring the 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) and 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonate radical cation (ABTS•+) scavenging activity. All compounds exhibited notable activity, compared with the positive control, l-Ascorbic acid. This study suggests that N. oppositifolia could be a promising source of secondary metabolites, some with lethal adulticidal effect against Ae. aegypti.
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Claims 4
Claim · model-written summary
Chromatographic purification of N. oppositifolia aerial parts yielded five phenolic compounds.
- Taxon
- Nuxia oppositifolia
Nuxia oppositifoliae0 - Organ / stage
- aerial partse0
- Outcome
- phenolic compoundse0
- Value
- fivee0
- Setting
- Saudie0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Chromatographic purification of the alcoholic extract from the aerial parts of the Saudi plant Nuxia oppositifolia (Hochst.), Benth., resulted in five isolated phenolic compounds”
Claim · model-written summary
Four compounds of Nuxia oppositifolia showed adulticidal activity against Aedes aegypti, with LD50 values of 2–2.3 μg/mosquito.
- Taxon
- Nuxia oppositifoliaNuxia oppositifoliae0
- Interactor
- Aedes aegypti
Aedes aegyptie2pest - Outcome
- adulticidal activitye1
- Value
- 2–2.3 μg/mosquitoe1
- Qualifier
- Four compoundse1
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Chromatographic purification of the alcoholic extract from the aerial parts of the Saudi plant Nuxia oppositifolia (Hochst.), Benth., resulted in five isolated phenolic compounds”
e1“Four compounds displayed adulticidal activity with LD50 values of 2–2.3 μg/mosquito”
e2“against the Yellow Fever mosquito, Aedes aegypti”
Claim · model-written summary
All tested compounds of N. oppositifolia showed notable free radical scavenging activity relative to l-ascorbic acid.
- Taxon
- Nuxia oppositifoliaNuxia oppositifoliae0
- Outcome
- Free radical scavenging propertiese3
- Direction
- notable activitye4
- Comparator
- positive control, l-Ascorbic acide4
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Chromatographic purification of the alcoholic extract from the aerial parts of the Saudi plant Nuxia oppositifolia (Hochst.), Benth., resulted in five isolated phenolic compounds”
e3“Free radical scavenging properties of the plant extracts and compounds (1–5) were evaluated”
e4“All compounds exhibited notable activity, compared with the positive control, l-Ascorbic acid”
Claim · model-written summary
N. oppositifolia could be a promising source of secondary metabolites.
- Taxon
- N. oppositifoliaNuxia oppositifoliae5
- Outcome
- promising source of secondary metabolitese5
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e5“This study suggests that N. oppositifolia could be a promising source of secondary metabolites”