Abstract
Valeriana carnosa SM (Caprifoliaceae), a native specie to Chile, is distributed from the Maule Region to Tierra del Fuego. The rhizomes and roots have been used to treat different diseases as an infusion, mainly due to the wide spectrum of chemical compounds with biological concern. This research consisted in carrying out a chemical characterization and evaluation of the antioxidant activity of V. carnosa in natural populations distributed in the central-southern part of Chile. The characterization of the extracts was carried out by GC-MS, showing that the rhizome extracts for both Laguna del Laja National Park and Malalcahuello National Reserve showed a higher percentage of sesquiterpenes, fatty acids and alkanes. On the other hand, leaf extracts for the Antuc o site presented a higher abundance of alkanes and fatty acids and for Malalcahuello, alkanes and phytosterols. Significant differences were demonstrated in the rhizome extracts according to the IC50 values (157.6 and 154.8 g/ml) at both sites, however, for the leaf extracts, Antuco presented a higher IC50 (450.33 g/ml). ABTS, showed that Antuco had a higher activity for both extracts, and the same trend was demonstrated in the polyphenol content, evaluated by the Folin-Ciocalteu method. In conclusion, the distribution of the species and, indirectly, the site conditions are considered relevant in this research, showing a direct incidence on the biological activity and chemical profile of V. carnosa.
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Claims 8
Claim · model-written summary
Rhizome extracts of Valeriana carnosa from Laguna del Laja National Park and Malalcahuello National Reserve showed a higher percentage of sesquiterpenes, fatty acids and alkanes.
- Taxon
- VALERIANA CARNOSA
Valeriana carnosat0 - Organ / stage
- rhizome extractse0
- Outcome
- percentage of sesquiterpenes, fatty acids and alkanese0
- Direction
- highere0
- Setting
- Laguna del Laja National Park and Malalcahuello National Reservee0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“the rhizome extracts for both Laguna del Laja National Park and Malalcahuello National Reserve showed a higher percentage of sesquiterpenes, fatty acids and alkanes”
t0“VALERIANA CARNOSA”
Claim · model-written summary
Leaf extracts of Valeriana carnosa from the Antuco site had a higher abundance of alkanes and fatty acids.
- Taxon
- VALERIANA CARNOSAValeriana carnosat0
- Organ / stage
- leaf extractse1
- Outcome
- abundance of alkanes and fatty acidse1
- Direction
- highere1
- Setting
- Antuc o sitee1
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e1“leaf extracts for the Antuc o site presented a higher abundance of alkanes and fatty acids and for Malalcahuello, alkanes and phytosterols”
t0“VALERIANA CARNOSA”
Claim · model-written summary
Leaf extracts of Valeriana carnosa from Malalcahuello were characterised by alkanes and phytosterols.
- Taxon
- VALERIANA CARNOSAValeriana carnosat0
- Organ / stage
- leaf extractse1
- Outcome
- alkanes and phytosterolse1
- Direction
- higherinferrede1
- Setting
- Malalcahuelloe1
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e1“leaf extracts for the Antuc o site presented a higher abundance of alkanes and fatty acids and for Malalcahuello, alkanes and phytosterols”
t0“VALERIANA CARNOSA”
Claim · model-written summary
Rhizome extracts showed significant differences in IC50 values (157.6 and 154.8 g/ml) between the two sites.
- Taxon
- VALERIANA CARNOSAValeriana carnosat0
- Organ / stage
- rhizome extractse2
- Outcome
- IC50 valuese2
- Value
- 157.6 and 154.8 g/mle2
Not reportedDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e2“Significant differences were demonstrated in the rhizome extracts according to the IC50 values (157.6 and 154.8 g/ml) at both sites”
t0“VALERIANA CARNOSA”
Claim · model-written summary
Leaf extracts from Antuco had a higher IC50 (450.33 g/ml).
- Taxon
- VALERIANA CARNOSAValeriana carnosat0
- Organ / stage
- leaf extractse3
- Outcome
- IC50e3
- Direction
- highere3
- Value
- 450.33 g/mle3
- Setting
- Antucoe3
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e3“for the leaf extracts, Antuco presented a higher IC50 (450.33 g/ml)”
t0“VALERIANA CARNOSA”
Claim · model-written summary
ABTS assays showed Antuco had a higher activity for both extracts.
- Taxon
- VALERIANA CARNOSAValeriana carnosat0
- Outcome
- activitye4
- Direction
- highere4
- Qualifier
- ABTSe4
- Setting
- Antucoe4
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e4“ABTS, showed that Antuco had a higher activity for both extracts”
t0“VALERIANA CARNOSA”
Claim · model-written summary
The same trend (higher at Antuco) was shown for polyphenol content measured by the Folin-Ciocalteu method.
- Taxon
- VALERIANA CARNOSAValeriana carnosat0
- Outcome
- polyphenol contente5
- Direction
- higherinferrede5
- Qualifier
- Folin-Ciocalteu methode5
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e5“the same trend was demonstrated in the polyphenol content, evaluated by the Folin-Ciocalteu method”
t0“VALERIANA CARNOSA”
Claim · model-written summary
The authors conclude that species distribution and, indirectly, site conditions have a direct incidence on the biological activity and chemical profile of V. carnosa.
- Taxon
- V. carnosaValeriana carnosae6
- Outcome
- biological activity and chemical profilee6
- Setting
- site conditionse6
Not reportedDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e6“the distribution of the species and, indirectly, the site conditions are considered relevant in this research, showing a direct incidence on the biological activity and chemical profile of V. carnosa”