Paper · 2019 · Letters in Applied NanoBioScience

The antioxidant activity and phytochemical analysis of medicinal plant Veronica biloba

Amir Hassan; Himayat Ullah; Muhammad Israr; et al.

6
claims
11
verbatim quotes
16
citations
1
research areas
✓
Open access

Abstract

A medicinal plant veronica genus has 450 well known species and found across both temperate and hemisphere region their 26 species are endemic and known in a total of 79 popular species and are widely utilized throughout the world due to important biological activities. In this study fully powdered uniform size specie veronica biloba plant taken in porous bag were manually subjected to soxhlet hot continuous process for cyclization of extraction using ethanol (300 mL) a concentrated dried extract obtained after solvent evaporation. Furthermore, liquid-liquid extracted fractions as water, dichloromethane, n-hexane, and ethyl acetate yields results found polar fraction with the highest percentage (water 47.51 %). The phytochemical screening of veronica biloba has shown all major compounds entirely present in extracts. One of the primitive phenolic compound flavonoid is present in plant and show potency towards antioxidants. All the extracted fractions of plant showed excellent antioxidant activity using a stable DPPH (1,1-diphenyl-2-picryl-hydrazyl) method at concentration (range from 31.25 to 500µg/mL). Primary our ethyl acetate extract fraction showed the highest inhibition potential at IC50 = 1.70±0.05µg/mL which is much closer to a standard positive control Propyl gallate showed IC50 = 1.6±0.05µg/mL percent potential. The purification and isolation of these extract areimportant which can provide us help in novel antioxidants discovery also natural antioxidants currently in cosmetics products, food and therapeutics health related products significantly demanded because they are very effective, efficient and harmless as compared to synthetic.

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Claims 6

Observationobservedoriginal resultmeasured

Claim · model-written summary

The water fraction had the highest extraction yield at 47.51%.

Taxon
veronica bilobaVeronica bilobae1
Material
watere0
Outcome
highest percentagee0
Direction
higheste0
Value
47.51 %e0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Veronica biloba
Veronica biloba · TaxonMatt Lavin from Bozeman, Montana, USA · CC BY-SA 2.0 · Wikimedia Commons ↗

Verbatim

e0

“polar fraction with the highest percentage (water 47.51 %)”

✓ located verbatim in the source · abstract, characters 661–719 · show in text ↑
e1

“veronica biloba plant”

✓ located verbatim in the source · abstract, characters 320–341 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

Phytochemical screening detected major compounds across Veronica biloba extracts.

Taxon
veronica bilobaVeronica bilobae0
Outcome
all major compounds entirely present in extractse0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Veronica biloba
Veronica biloba · TaxonMatt Lavin from Bozeman, Montana, USA · CC BY-SA 2.0 · Wikimedia Commons ↗

Verbatim

e0

“The phytochemical screening of veronica biloba has shown all major compounds entirely present in extracts”

✓ located verbatim in the source · abstract, characters 721–826 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

Flavonoid was present in Veronica biloba.

Taxon
veronica bilobaVeronica bilobae1
Outcome
flavonoid is present in plante0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Veronica biloba
Veronica biloba · TaxonMatt Lavin from Bozeman, Montana, USA · CC BY-SA 2.0 · Wikimedia Commons ↗

Verbatim

e0

“phenolic compound flavonoid is present in plant”

✓ located verbatim in the source · abstract, characters 849–896 · show in text ↑
e1

“veronica biloba plant”

✓ located verbatim in the source · abstract, characters 320–341 · show in text ↑
Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

All extracted Veronica biloba fractions showed antioxidant activity by DPPH at 31.25 to 500µg/mL.

Taxon
veronica bilobaVeronica bilobae1
Outcome
antioxidant activitye0
Value
31.25 to 500µg/mLe0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Veronica biloba
Veronica biloba · TaxonMatt Lavin from Bozeman, Montana, USA · CC BY-SA 2.0 · Wikimedia Commons ↗

Verbatim

e0

“All the extracted fractions of plant showed excellent antioxidant activity using a stable DPPH (1,1-diphenyl-2-picryl-hydrazyl) method at concentration (range from 31.25 to 500µg/mL)”

✓ located verbatim in the source · abstract, characters 936–1118 · show in text ↑
e1

“veronica biloba plant”

✓ located verbatim in the source · abstract, characters 320–341 · show in text ↑
Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

The ethyl acetate fraction had the highest inhibition potential with IC50 1.70±0.05µg/mL.

Taxon
veronica bilobaVeronica bilobae1
Material
ethyl acetate extract fractione0
Outcome
inhibition potentiale0
Direction
higheste0
Value
IC50 = 1.70±0.05µg/mLe0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Veronica biloba
Veronica biloba · TaxonMatt Lavin from Bozeman, Montana, USA · CC BY-SA 2.0 · Wikimedia Commons ↗

Verbatim

e0

“ethyl acetate extract fraction showed the highest inhibition potential at IC50 = 1.70±0.05µg/mL”

✓ located verbatim in the source · abstract, characters 1132–1227 · show in text ↑
e1

“veronica biloba plant”

✓ located verbatim in the source · abstract, characters 320–341 · show in text ↑
Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

Ethyl acetate fraction inhibition potential was close to propyl gallate control IC50 1.6±0.05µg/mL.

Taxon
veronica bilobaVeronica bilobae1
Material
ethyl acetate extract fractione0
Outcome
inhibition potentiale0
Direction
closere0
Value
IC50 = 1.70±0.05µg/mLe0
Qualifier
IC50 = 1.6±0.05µg/mLe0
Comparator
Propyl gallatee0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Veronica biloba
Veronica biloba · TaxonMatt Lavin from Bozeman, Montana, USA · CC BY-SA 2.0 · Wikimedia Commons ↗

Verbatim

e0

“ethyl acetate extract fraction showed the highest inhibition potential at IC50 = 1.70±0.05µg/mL which is much closer to a standard positive control Propyl gallate showed IC50 = 1.6±0.05µg/mL”

✓ located verbatim in the source · abstract, characters 1132–1322 · show in text ↑
e1

“veronica biloba plant”

✓ located verbatim in the source · abstract, characters 320–341 · show in text ↑