Abstract
This study aimed to identify the chemical composition, and investigation of antioxidant and antibacterial activity of Zygophyllum fabago, Zygophyllum eurypterum, Zygophyllum propinquum and Zygophyllum megacarpum extracts against human pathogenic bacterial. The samples were collected from West Azarbaijan province and were analyzed in biotechnology department of Bu Ali Sina University, Iran. The antibacterial activity by agar well diffusion assay, minimum bactericidal concentrations (MBCs) and minimum inhibitory concentrations (MICs) by the serial dilution method and free radical activity by 2, 2-diphenyl-1-picrylhydrazyl (DPPH) were measured. Next, the phenolic and flavonoid contents were calculated by Folin-Ciocalteu and Aluminum Chloride methods, respectively, and the presence of the phytochemical compounds including alkaloids, saponins, and tannins were tested. In addition, chemical compositions analysis was done using a GCMS. The major components including as ar-curcumene (17.18%), methyl ester (21.53%), caryophyllène (17.07%), and carvacrol (23.71%) were dominant in Z. fabago, Z. eurypterum, Z. propinquum and Z. megacarpum, respectively. The highest sensitivity was observed on S. epidermidis with MIC of 3.125% on flower extract of Z. fabago. The most potent radical scavenging activity belonged to the flower extract of Z.megacarpum. The highest phenolic and flavonoid contents were obtained in Z. fabago root extract as 301.04 mgGA/DWg and 8.04 mgQ/DWg, respectively as well as carvacrol was determined as the dominant compound. Based on the findings, Zygophyllum spp can be suggested for producing natural drugs and antimicrobial agents.
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Claims 8
Claim · model-written summary
Ar-curcumene was dominant in Z. fabago at 17.18%.
- Taxon
- Z. fabago
Zygophyllum fabagoe0 - Outcome
- ar-curcumenee0
- Value
- 17.18%e0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“ar-curcumene (17.18%), methyl ester (21.53%), caryophyllène (17.07%), and carvacrol (23.71%) were dominant in Z. fabago, Z. eurypterum, Z. propinquum and Z. megacarpum, respectively”
Claim · model-written summary
Methyl ester was dominant in Z. eurypterum at 21.53%.
- Taxon
- Z. eurypterumZygophyllum eurypterume0
- Outcome
- methyl estere0
- Value
- 21.53%e0
Verbatim
e0“ar-curcumene (17.18%), methyl ester (21.53%), caryophyllène (17.07%), and carvacrol (23.71%) were dominant in Z. fabago, Z. eurypterum, Z. propinquum and Z. megacarpum, respectively”
Claim · model-written summary
Caryophyllène was dominant in Z. propinquum at 17.07%.
- Taxon
- Z. propinquumTetraena propinquae0
- Outcome
- caryophyllènee0
- Value
- 17.07%e0
Verbatim
e0“ar-curcumene (17.18%), methyl ester (21.53%), caryophyllène (17.07%), and carvacrol (23.71%) were dominant in Z. fabago, Z. eurypterum, Z. propinquum and Z. megacarpum, respectively”
Claim · model-written summary
Carvacrol was dominant in Z. megacarpum at 23.71%.
- Taxon
- Z. megacarpumZygophyllum megacarpume0
- Outcome
- carvacrole0
- Value
- 23.71%e0
Verbatim
e0“ar-curcumene (17.18%), methyl ester (21.53%), caryophyllène (17.07%), and carvacrol (23.71%) were dominant in Z. fabago, Z. eurypterum, Z. propinquum and Z. megacarpum, respectively”
Claim · model-written summary
The flower extract of Z. megacarpum had the most potent radical scavenging activity.
- Taxon
- Z.megacarpumZygophyllum megacarpume0
- Organ / stage
- flowere0
- Outcome
- radical scavenging activitye0
- Direction
- most potente0
Verbatim
e0“The most potent radical scavenging activity belonged to the flower extract of Z.megacarpum”
Claim · model-written summary
Z. fabago root extract had the highest phenolic content, 301.04 mgGA/DWg.
- Taxon
- Z. fabagoZygophyllum fabagoe0
- Organ / stage
- roote0
- Outcome
- phenolice0
- Direction
- higheste0
- Value
- 301.04 mgGA/DWge0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“The highest phenolic and flavonoid contents were obtained in Z. fabago root extract as 301.04 mgGA/DWg and 8.04 mgQ/DWg”
Claim · model-written summary
Z. fabago root extract had the highest flavonoid content, 8.04 mgQ/DWg.
- Taxon
- Z. fabagoZygophyllum fabagoe0
- Organ / stage
- roote0
- Outcome
- flavonoide0
- Direction
- higheste0
- Value
- 8.04 mgQ/DWge0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“The highest phenolic and flavonoid contents were obtained in Z. fabago root extract as 301.04 mgGA/DWg and 8.04 mgQ/DWg”
Claim · model-written summary
Carvacrol was determined to be a dominant compound.
Not reportedTaxon
Verbatim
e0“carvacrol was determined as the dominant compound”