Abstract
This work aims to evaluate the phenolic compounds, and assess the antioxidant, acute oral toxicity, and the antidiabetic effects of an aqueous extract from the edible parts of Mesembryanthemum cryptanthum Hook.f. (MCHAE) collected in Dakhla-Oued Ed-Dahab region of Morocco. Nine polyphenolic compounds, analysed by HPLC-PDA/ESI-MS, were positively identified. MCHAE revealed an inhibitory concentration (IC50) of 547.63 µg/mL, compared to butylhydroxytoluene (IC50 = 13.63 µg/mL). According to the acute oral toxicity study, an LD50 value was between 2000 and 5000 mg/kg b.w. Further, the MCHAE, at a dose of 80 mg/kg, resulted to possess an antidiabetic effect in STZ-treated diabetic rats and hypoglycaemic effect in normal rats. Therefore, the edible parts of Mesembryanthemum cryptanthum Hook.f. can be employed as natural alternative medicine to treat diabetes mellitus.
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Claims 1
Claim · model-written summary
Nine polyphenolic compounds were identified in the edible-part extract.
- Taxon
- Mesembryanthemum cryptanthum Hook.f.
Mesembryanthemum cryptanthumt0 - Outcome
- polyphenolic compoundse0
- Value
- Ninee0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Nine polyphenolic compounds, analysed by HPLC-PDA/ESI-MS, were positively identified.”
t0“Mesembryanthemum cryptanthum Hook.f.”