Paper · 2025 · Asian Journal of Pharmaceutical and Clinical Research

INSIGHTS INTO THE ETHNOPHARMACOLOGICAL PROPERTIES OF COMBRETUM APICULATUM SOND. (FAMILY COMBRETACEAE): NARRATIVE REVIEW

ALFRED MAROYI

6
claims
12
verbatim quotes
0
citations
2
research areas
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Open access · cc-by

Abstract

Combretum apiculatum sond. is a small to medium-sized deciduous tree which is used in traditional medicine in several countries in tropical Africa. This study was aimed at providing information on the ethnobotany, medicinal uses, phytochemistry, and pharmacological properties of C. apiculatum. Information about ethnobotanical applications, phytochemistry, and pharmacological properties of C. apiculatum was collected from the several online databases such as PubMed®, Google Scholar, ScienceDirect®, Web of Science, SpringerLink®, SciELO, and Scopus®, as well as pre-electronic literature sources which included books, book chapters and other scientific publications obtained from the university library. The findings highlight the use of the bark, fruits, leaves, roots, seeds, stems, and stem bark of C. apiculatum as traditional medicine for bilharzia, conjunctivitis, gastro-intestinal problems, infertility in women, leprosy, respiratory infections, sexually transmitted infections, and skin diseases. Chemical compounds identified from C. apiculatum include amino acids, bibenzyls (dihydrostilbenes), chalcones, flavonoids, phenanthrenes, alkaloids, lignin, phenolics, terpenoids, essential oils, resin acids, lipids, pectins, carboxylated, and hydroxylated polysaccharides. The crude extracts of C. apiculatum exhibited antibacterial, anthelmintic, antifungal, antioxidant, anti-inflammatory, antiproliferative, and cytotoxicity activities. Future studies should focus on detailed ethnopharmacological evaluation of C. apiculatum, particularly its phytochemistry, biological activities, and toxicological assessments, in vivo and clinical studies.

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Claims 6

Observationobservedreview summarypositivebasis n/a

Claim · model-written summary

Crude extracts of Combretum apiculatum showed antibacterial, anthelmintic and antifungal activities.

Taxon
Combretum apiculatumCombretum apiculatume0
Treatment
crude extractse1
Outcome
antibacterial, anthelmintic, antifungale1

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Combretum apiculatum
Combretum apiculatum · TaxonJMK · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“Combretum apiculatum sond. is a small to medium-sized deciduous tree which is used in traditional medicine in several countries in tropical Africa”

✓ located verbatim in the source · abstract, characters 0–146 · show in text ↑
e1

“The crude extracts of C. apiculatum exhibited antibacterial, anthelmintic, antifungal, antioxidant, anti-inflammatory, antiproliferative, and cytotoxicity activities”

✓ located verbatim in the source · abstract, characters 1284–1449 · show in text ↑
Observationobservedreview summarypositivebasis n/a

Claim · model-written summary

Crude extracts of Combretum apiculatum showed antioxidant, anti-inflammatory and antiproliferative activities.

Taxon
Combretum apiculatumCombretum apiculatume0
Treatment
crude extractse1
Outcome
antioxidant, anti-inflammatory, antiproliferativee1

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Combretum apiculatum
Combretum apiculatum · TaxonJMK · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“Combretum apiculatum sond. is a small to medium-sized deciduous tree which is used in traditional medicine in several countries in tropical Africa”

✓ located verbatim in the source · abstract, characters 0–146 · show in text ↑
e1

“The crude extracts of C. apiculatum exhibited antibacterial, anthelmintic, antifungal, antioxidant, anti-inflammatory, antiproliferative, and cytotoxicity activities”

✓ located verbatim in the source · abstract, characters 1284–1449 · show in text ↑
Observationobservedreview summarybasis n/a

Claim · model-written summary

Crude extracts of Combretum apiculatum showed cytotoxicity.

Taxon
Combretum apiculatumCombretum apiculatume0
Treatment
crude extractse1
Outcome
cytotoxicitye1

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Combretum apiculatum
Combretum apiculatum · TaxonJMK · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“Combretum apiculatum sond. is a small to medium-sized deciduous tree which is used in traditional medicine in several countries in tropical Africa”

✓ located verbatim in the source · abstract, characters 0–146 · show in text ↑
e1

“The crude extracts of C. apiculatum exhibited antibacterial, anthelmintic, antifungal, antioxidant, anti-inflammatory, antiproliferative, and cytotoxicity activities”

✓ located verbatim in the source · abstract, characters 1284–1449 · show in text ↑
Observationobservedreview summarybasis n/a

Claim · model-written summary

Bark, fruits, leaves, roots, seeds, stems and stem bark of Combretum apiculatum are used as traditional medicine for several conditions.

Taxon
Combretum apiculatumCombretum apiculatume0
Organ / stage
bark, fruits, leaves, roots, seeds, stems, and stem barke1
Outcome
traditional medicinee1
Qualifier
bilharzia, conjunctivitis, gastro-intestinal problemse1

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Combretum apiculatum
Combretum apiculatum · TaxonJMK · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“Combretum apiculatum sond. is a small to medium-sized deciduous tree which is used in traditional medicine in several countries in tropical Africa”

✓ located verbatim in the source · abstract, characters 0–146 · show in text ↑
e1

“The findings highlight the use of the bark, fruits, leaves, roots, seeds, stems, and stem bark of C. apiculatum as traditional medicine for bilharzia, conjunctivitis, gastro-intestinal problems”

✓ located verbatim in the source · abstract, characters 708–901 · show in text ↑
Observationobservedreview summarybasis n/a

Claim · model-written summary

Chemical compounds identified from Combretum apiculatum include amino acids, bibenzyls, chalcones and other classes.

Taxon
Combretum apiculatumCombretum apiculatume0
Outcome
Chemical compoundse1
Qualifier
amino acids, bibenzyls (dihydrostilbenes), chalconese1

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Combretum apiculatum
Combretum apiculatum · TaxonJMK · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“Combretum apiculatum sond. is a small to medium-sized deciduous tree which is used in traditional medicine in several countries in tropical Africa”

✓ located verbatim in the source · abstract, characters 0–146 · show in text ↑
e1

“Chemical compounds identified from C. apiculatum include amino acids, bibenzyls (dihydrostilbenes), chalcones”

✓ located verbatim in the source · abstract, characters 1010–1119 · show in text ↑
Recommendationauthor interpretationreview summarybasis n/a

Claim · model-written summary

Future studies should carry out a detailed ethnopharmacological evaluation of Combretum apiculatum.

Taxon
Combretum apiculatumCombretum apiculatume0
Outcome
detailed ethnopharmacological evaluation of C. apiculatume1

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Combretum apiculatum
Combretum apiculatum · TaxonJMK · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“Combretum apiculatum sond. is a small to medium-sized deciduous tree which is used in traditional medicine in several countries in tropical Africa”

✓ located verbatim in the source · abstract, characters 0–146 · show in text ↑
e1

“Future studies should focus on detailed ethnopharmacological evaluation of C. apiculatum”

✓ located verbatim in the source · abstract, characters 1451–1539 · show in text ↑