Abstract
ABSTRACT Phoenix dactylifera L. (Ghars variety) seeds, widely available in Algeria, represent a valuable natural resource. Their rich phytochemical composition presents promising potential for applications in health and skincare. This study evaluates the phytochemical profile and biological activities of ethanolic extracts (EE) from Ghars date seeds and assesses the antimicrobial efficacy of a formulated cosmetic cream. Ethanolic extraction yielded 11.425% EE. Phytochemical screening, total flavonoid content (TFC), and total phenolic content (TPC) were determined. Antioxidant activity was evaluated using ferric reducing antioxidant power (RAP) and DPPH assays. Anti‐inflammatory activity was assessed via membrane stabilization, and the antimicrobial potential of the EE‐based cream was tested against selected bacterial strains. The EE exhibited high flavonoid (68.81 mg/mL) and phenolic content (118.6 mg/mL). Antioxidant assays showed strong activity, with IC 50 values of 47.86 μg/mL (FRAP) and 35.85 μg/mL (DPPH). The extract demonstrated notable anti‐inflammatory effects. The EE‐based cream displayed significant antimicrobial activity, with inhibition zones up to 27 mm against Bacillus subtilis and marked effects against Staphylococcus aureus and Pseudomonas aeruginosa . Ghars date seed EE shows strong antioxidant, anti‐inflammatory, and antimicrobial properties, supporting its use as a natural ingredient in cosmetic and healthcare formulations.
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Claims 10
Claim · model-written summary
Ethanolic extraction of Ghars date seeds yielded 11.425% extract.
- Taxon
- Phoenix dactylifera L.
Phoenix dactyliferae1 - Material
- Ghars varietye1
- Organ / stage
- seedse1
- Outcome
- EEe0
- Value
- 11.425%e0
- Setting
- Algeriae1
Not reportedDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Ethanolic extraction yielded 11.425% EE.”
e1“Phoenix dactylifera L. (Ghars variety) seeds, widely available in Algeria”
Claim · model-written summary
The extract had high flavonoid content of 68.81 mg/mL.
- Taxon
- Phoenix dactylifera L.Phoenix dactyliferae1
- Material
- Ghars varietye1
- Organ / stage
- seedse1
- Outcome
- flavonoide0
- Direction
- highe0
- Value
- 68.81 mg/mLe0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“The EE exhibited high flavonoid (68.81 mg/mL) and phenolic content (118.6 mg/mL).”
e1“Phoenix dactylifera L. (Ghars variety) seeds, widely available in Algeria”
Claim · model-written summary
The extract had high phenolic content of 118.6 mg/mL.
- Taxon
- Phoenix dactylifera L.Phoenix dactyliferae1
- Material
- Ghars varietye1
- Organ / stage
- seedse1
- Outcome
- phenolic contente0
- Direction
- highe0
- Value
- 118.6 mg/mLe0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“The EE exhibited high flavonoid (68.81 mg/mL) and phenolic content (118.6 mg/mL).”
e1“Phoenix dactylifera L. (Ghars variety) seeds, widely available in Algeria”
Claim · model-written summary
The extract showed strong antioxidant activity with FRAP IC50 of 47.86 μg/mL.
- Taxon
- Phoenix dactylifera L.Phoenix dactyliferae1
- Outcome
- IC 50e0
- Value
- 47.86 μg/mLe0
- Qualifier
- FRAPe0
Not reportedDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Antioxidant assays showed strong activity, with IC 50 values of 47.86 μg/mL (FRAP) and 35.85 μg/mL (DPPH).”
e1“Phoenix dactylifera L. (Ghars variety) seeds, widely available in Algeria”
Claim · model-written summary
The extract showed strong antioxidant activity with DPPH IC50 of 35.85 μg/mL.
- Taxon
- Phoenix dactylifera L.Phoenix dactyliferae1
- Outcome
- IC 50e0
- Value
- 35.85 μg/mLe0
- Qualifier
- DPPHe0
Not reportedDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Antioxidant assays showed strong activity, with IC 50 values of 47.86 μg/mL (FRAP) and 35.85 μg/mL (DPPH).”
e1“Phoenix dactylifera L. (Ghars variety) seeds, widely available in Algeria”
Claim · model-written summary
The extract demonstrated notable anti-inflammatory effects.
- Outcome
- notable anti‐inflammatory effectse0
Not reportedTaxonDirection
Verbatim
e0“The extract demonstrated notable anti‐inflammatory effects.”
Claim · model-written summary
The extract-based cream significantly inhibited Bacillus subtilis with inhibition zones up to 27 mm.
- Taxon
- Bacillus subtilis
Bacillus subtilise0 - Treatment
- EE‐based creame0
- Outcome
- inhibition zonese0
- Value
- 27 mme0
- Qualifier
- up toe0
Not reportedDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“The EE‐based cream displayed significant antimicrobial activity, with inhibition zones up to 27 mm against Bacillus subtilis and marked effects against Staphylococcus aureus and Pseudomonas aeruginosa .”
Claim · model-written summary
The extract-based cream had marked effects against Staphylococcus aureus.
- Taxon
- Staphylococcus aureus
Staphylococcus aureuse0 - Treatment
- EE‐based creame0
- Outcome
- marked effectse0
Not reportedDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“The EE‐based cream displayed significant antimicrobial activity, with inhibition zones up to 27 mm against Bacillus subtilis and marked effects against Staphylococcus aureus and Pseudomonas aeruginosa .”
Claim · model-written summary
The extract-based cream had marked effects against Pseudomonas aeruginosa.
- Taxon
- Pseudomonas aeruginosa
Pseudomonas aeruginosae0 - Treatment
- EE‐based creame0
- Outcome
- marked effectse0
Not reportedDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“The EE‐based cream displayed significant antimicrobial activity, with inhibition zones up to 27 mm against Bacillus subtilis and marked effects against Staphylococcus aureus and Pseudomonas aeruginosa .”
Claim · model-written summary
The authors support using Ghars date seed extract as a natural ingredient in cosmetic and healthcare formulations.
Verbatim
e0“Ghars date seed EE shows strong antioxidant, anti‐inflammatory, and antimicrobial properties, supporting its use as a natural ingredient in cosmetic and healthcare formulations.”