EVALUATION OF PHYTOCHEMICAL SCREENING AND THROMBOLYTIC ACTIVITY OF MORINGA LEAVES

Abstract

Moringa oleifera, commonly known as the drumstick tree, is widely utilized in traditional medicine due to its medicinally active constituents. Various parts of the plant exhibit antioxidant, anti-inflammatory, antimicrobial, anticancer, and cardioprotective activities. Cardiovascular disorders are a major cause of morbidity and mortality worldwide, and thrombolysis (clot dissolution) is a critical therapeutic target. Hence, evaluation of thrombolytic potential from natural sources is of high interest.Medicinal plants have been used for centuries in traditional systems of medicine for the treatment of various diseases. However, scientific validation and phytochemical characterization are essential to ensure their efficacy and safety. The present study aimed to investigate the phytochemical profile of Cissus pallida leaves, with a particular focus on tannin content. Specimens were collected from the Nallamala forest region (Kurnool, Nellore), authenticated by a taxonomist, and subjected to successive solvent extraction using petroleum ether, chloroform, and methanol. Preliminary phytochemical screening revealed the presence of steroids, alkaloids, flavonoids, tannins, and phenolics in varying amounts. Thin-layer chromatography (TLC) confirmed the presence of tannins exclusively in the methanolic extract. Quantitative estimation indicated that the leaves contain 3.14% w/w total tannins. These results suggest that Cissus pallida leaves may be a valuable source of tannins, which are known for their antioxidant, antimicrobial, and anti-inflammatory properties.

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