Abstract
• The desert moss S. caninervis retains an ancestral and diverse aquaporin repertoire, from which ScAQP1 emerges as a central hub. • ScAQP1 confers robust desiccation tolerance not only by enhancing water conservation but also by activating coordinated antioxidant defenses, a multifaceted mechanism that is functionally transferable to Arabidopsis . • ScAQP1 is involved in mediating H 2 O 2 homeostasis, likely through peroxiporin-like activity, contributing to cellular protection and showcasing its potential as a genetic resource for engineering climate-resilient crops. Aquaporins (AQPs) are crucial for plant drought adaptation, yet their contributions to the extreme resilience of desiccation-tolerant plants remain largely unclear. This study presents a comprehensive genome-wide analysis of AQPs in the desert moss Syntrichia caninervis , identifying 18 members across seven subfamilies, including ancient lineages that have been largely lost in vascular plants. Integrated transcriptomic and network analysis identified ScAQP1 as a core hub in the stress-responsive network. Functional characterization in both S. caninervis and Arabidopsis thaliana demonstrated that ScAQP1 confers robust drought tolerance by improving water retention and mitigating oxidative stress through enhanced antioxidant systems and proline accumulation. From a mechanistic perspective, the ScAQP1 overexpression yeast experiment indicated that ScAQP1 is involved in regulating the intracellular H 2 O 2 balance. These findings reveal a mechanism in S. caninervis where ScAQP1 functionally integrates hydraulic regulation with redox signaling, distinguishing it from typical water channels. This research provides novel insights into the evolution of AQPs in early land plants and validates ScAQP1 as a potent candidate for engineering stress resilient crops.
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Claims 6
Claim · model-written summary
Genome-wide analysis of S. caninervis aquaporins identified 18 AQP members across seven subfamilies.
- Taxon
- Syntrichia caninervis
Syntrichia caninervise1 - Outcome
- AQPse1
- Value
- 18 memberse1
- Qualifier
- across seven subfamiliese1
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e1“genome-wide analysis of AQPs in the desert moss Syntrichia caninervis , identifying 18 members across seven subfamilies”
Claim · model-written summary
Integrated transcriptomic and network analysis identified ScAQP1 as a core hub in the stress-responsive network of S. caninervis.
- Taxon
- Syntrichia caninervisSyntrichia caninervise1
- Gene
- ScAQP1e2
- Outcome
- core hube2
- Qualifier
- stress-responsive networke2
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e1“genome-wide analysis of AQPs in the desert moss Syntrichia caninervis , identifying 18 members across seven subfamilies”
e2“Integrated transcriptomic and network analysis identified ScAQP1 as a core hub in the stress-responsive network”
Claim · model-written summary
ScAQP1 confers drought tolerance when expressed in Arabidopsis thaliana and S. caninervis.
- Taxon
- Arabidopsis thaliana
Arabidopsis thalianae3 - Gene
- ScAQP1e3
- Outcome
- drought tolerancee3
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e3“Functional characterization in both S. caninervis and Arabidopsis thaliana demonstrated that ScAQP1 confers robust drought tolerance by improving water retention and mitigating oxidative stress through enhanced antioxidant systems and proline accumulation”
Claim · model-written summary
ScAQP1 mitigates oxidative stress in S. caninervis through enhanced antioxidant systems and proline accumulation.
- Taxon
- S. caninervisSyntrichia caninervise3
- Gene
- ScAQP1e3
- Outcome
- oxidative stresse3
- Qualifier
- through enhanced antioxidant systems and proline accumulatione3
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e3“Functional characterization in both S. caninervis and Arabidopsis thaliana demonstrated that ScAQP1 confers robust drought tolerance by improving water retention and mitigating oxidative stress through enhanced antioxidant systems and proline accumulation”
Claim · model-written summary
ScAQP1 is involved in mediating H2O2 homeostasis, likely through peroxiporin-like activity.
- Taxon
- S. caninervisSyntrichia caninervise3
- Gene
- ScAQP1e4
- Outcome
- H 2 O 2 homeostasise4
- Qualifier
- likely through peroxiporin-like activitye4
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e3“Functional characterization in both S. caninervis and Arabidopsis thaliana demonstrated that ScAQP1 confers robust drought tolerance by improving water retention and mitigating oxidative stress through enhanced antioxidant systems and proline accumulation”
e4“ScAQP1 is involved in mediating H 2 O 2 homeostasis, likely through peroxiporin-like activity”
Claim · model-written summary
ScAQP1 functionally integrates hydraulic regulation with redox signaling in S. caninervis, distinguishing it from typical water channels.
- Taxon
- S. caninervisSyntrichia caninervise5
- Gene
- ScAQP1e5
- Outcome
- hydraulic regulation with redox signalinge5
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e5“These findings reveal a mechanism in S. caninervis where ScAQP1 functionally integrates hydraulic regulation with redox signaling, distinguishing it from typical water channels”