Abstract
The study focuses on the Invitro anti-dandruff study and phytochemical screening of aqueous extract of Allamanda cathartica L. leaves dandruff is a common scalp disorder primarily caused by the lipophilic yeast Malassezia furfur. Although several synthetic antifungal agents are available for its treatment, prolonged use may lead to adverse effects and the development of resistance. This has increased interest in herbal remedies as safer alternatives. The present study was undertaken to evaluate the antidandruff potential of Allamanda cathartica L. leaf extract and to investigate its phytochemical constituents. The study includes leaves collection, authentication, shade dry, powdering and extraction using distilled water by the Maceration method. Preliminary phytochemical screening revealed the presence of carbohydrates, alkaloids, glycosides, flavonoids, tannins and lipids. The anti-dandruff activity of the aqueous extract assessed against Malassezia furfur using the agar well diffusion method, with Ketoconazole as the standard drug. The extract exhibits a measurable zone of inhibition at higher concentrations, indicating significant anti-dandruff activity. The study confirms that Allamanda cathartica L. possesses promising anti-dandruff potential may serve as natural, effective alternative for the management of dandruff, subject to further formulation development and clinical evaluation.
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Claims 4
Claim · model-written summary
The Allamanda cathartica leaf extract contained carbohydrates, alkaloids and glycosides.
- Taxon
- Allamanda cathartica L.
Allamanda catharticae1 - Organ / stage
- leafe1
- Outcome
- carbohydrates, alkaloids, glycosidese0
Not reportedDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Preliminary phytochemical screening revealed the presence of carbohydrates, alkaloids, glycosides, flavonoids, tannins and lipids.”
e1“Allamanda cathartica L. leaf extract”
Claim · model-written summary
The Allamanda cathartica leaf extract contained flavonoids, tannins and lipids.
- Taxon
- Allamanda cathartica L.Allamanda catharticae1
- Organ / stage
- leafe1
- Outcome
- flavonoids, tannins and lipidse0
Not reportedDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Preliminary phytochemical screening revealed the presence of carbohydrates, alkaloids, glycosides, flavonoids, tannins and lipids.”
e1“Allamanda cathartica L. leaf extract”
Claim · model-written summary
At higher concentrations, the aqueous extract inhibited Malassezia furfur, indicating significant anti-dandruff activity.
- Taxon
- Malassezia furfur
Malassezia furfure1 - Treatment
- aqueous extracte1
- Outcome
- zone of inhibitione0
- Qualifier
- higher concentrationse0
- Comparator
- Ketoconazolee1
Not reportedDirection
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“The extract exhibits a measurable zone of inhibition at higher concentrations, indicating significant anti-dandruff activity.”
e1“The anti-dandruff activity of the aqueous extract assessed against Malassezia furfur using the agar well diffusion method, with Ketoconazole as the standard drug.”
Claim · model-written summary
The authors propose Allamanda cathartica as an anti-dandruff alternative subject to formulation development and clinical evaluation.
- Taxon
- Allamanda cathartica L.Allamanda catharticae0
- Outcome
- natural, effective alternative for the management of dandruffe0
- Qualifier
- subject to further formulation development and clinical evaluatione0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“The study confirms that Allamanda cathartica L. possesses promising anti-dandruff potential may serve as natural, effective alternative for the management of dandruff, subject to further formulation development and clinical evaluation.”