Paper · 2026 · Zenodo (CERN European Organization for Nuclear Research)

ISOLATION AND STRUCTURAL DETERMINATION OF MYO-INOSITOL FROM COELOCARYON PREUSSII FRUIT SHELLS: ANTIOXIDANT ACTIVITY

Yao Yao Jean Gervais-Cédric1, Kabran Aka Faustin1*, Dibi Konan Jacques2, Ambeu-Loko N'Ta Christelle Melissa1, Koné Maïmouna Coura3, Cebriàn-Torrejòn Gérardo4

3
claims
7
verbatim quotes
0
citations
2
research areas
✓
Open access · cc-by

Abstract

The methanolic extract of the fresh fruit shells of Coelocaryon preussii was studied to highlight its bioactive components. The investigation led to the isolation and identification of an inositol derivative named myo-inositol. The structure of this compound which was isolated for the first time from this species was established on the basis of its IR, NMR and Mass analyses. The evaluation of the antioxidant activity of this compound using the DPPH method gave a relatively interesting activity (IC50 = 34.8 µg/mL) compared to the reference compounds, vitamin C (IC50 = 5.3 µg/mL) and quercetin (IC50 = 3.1 µg/mL).

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Claims 3

Observationobservedoriginal resultmeasured

Claim · model-written summary

Myo-inositol was isolated and identified from Coelocaryon preussii fruit shells for the first time in this species.

Taxon
Coelocaryon preussiiCoelocaryon preussiie0
Organ / stage
fruit shellse0
Outcome
isolation and identification of an inositol derivative named myo-inositole1
Qualifier
first time from this speciese2

Verbatim

e0

“fresh fruit shells of Coelocaryon preussii”

✓ located verbatim in the source · abstract, characters 30–72 · show in text ↑
e1

“isolation and identification of an inositol derivative named myo-inositol”

✓ located verbatim in the source · abstract, characters 153–226 · show in text ↑
e2

“isolated for the first time from this species”

✓ located verbatim in the source · abstract, characters 269–314 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

The isolated compound had DPPH antioxidant activity with IC50 of 34.8 µg/mL, compared with vitamin C at 5.3 µg/mL.

Taxon
Coelocaryon preussiiCoelocaryon preussiie0
Outcome
antioxidant activitye1
Value
34.8 µg/mLe1
Qualifier
IC50 = 5.3 µg/mLe1
Comparator
vitamin Ce1

Verbatim

e0

“Coelocaryon preussii”

✓ located verbatim in the source · abstract, characters 52–72 · show in text ↑
e1

“antioxidant activity of this compound using the DPPH method gave a relatively interesting activity (IC50 = 34.8 µg/mL) compared to the reference compounds, vitamin C (IC50 = 5.3 µg/mL) and quercetin (IC50 = 3.1 µg/mL)”

✓ located verbatim in the source · abstract, characters 400–617 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

The isolated compound had DPPH antioxidant activity with IC50 of 34.8 µg/mL, compared with quercetin at 3.1 µg/mL.

Taxon
Coelocaryon preussiiCoelocaryon preussiie0
Outcome
antioxidant activitye1
Value
34.8 µg/mLe1
Qualifier
IC50 = 3.1 µg/mLe1
Comparator
quercetine1

Verbatim

e0

“Coelocaryon preussii”

✓ located verbatim in the source · abstract, characters 52–72 · show in text ↑
e1

“antioxidant activity of this compound using the DPPH method gave a relatively interesting activity (IC50 = 34.8 µg/mL) compared to the reference compounds, vitamin C (IC50 = 5.3 µg/mL) and quercetin (IC50 = 3.1 µg/mL)”

✓ located verbatim in the source · abstract, characters 400–617 · show in text ↑