Paper · 2026 · Journal of Drug Delivery and Therapeutics

Ethnobotanical study and safety assessment of medicinal plants from Guiriko region of Burkina Faso used for their doping properties

Clarisse Ouédraogo; Windmi Kagambéga; Hadidiatou Belem; et al.

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claims
11
verbatim quotes
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citations
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research areas
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Open access · cc-by-nc

Abstract

The use of medicinal plants remains an essential practice in sub-Saharan Africa, where they constitute a major therapeutic and socio-cultural resource objective of the study was to investigate medicinal plants used for doping in the city of Bobo-Dioulasso. Methods: To do this, a semi-structured ethnobotanical survey was first conducted among traditional practitioners. Phytochemical compositions of the plants were analyzed using spectrophotometry. Finally, the acute toxicity of the doping plants was studied by administering a single dose of 5000 mg/kg body weight to NRMI mice, which were observed for 14 days. Results: A total of 50 traditional practitioners and herbalists were interviewed and 25 plants species belonging to 17 botanical families were identified. Based on the frequency of citation, the species Martynia annua Lin (Martyniaceae), Securidaca longepedunculata Fresen (Polygalaceae), and Leptadenia hastata (Pesr.) Decne (Asclepiadaceae) were selected for further study. The leaves (55.13%) and root bark (21.79%) were the most used parts. The phytochemical study revealed the presence of phenolic compounds such as polyphenols, total flavonoids and tannins. The extracts exhibited antioxidant activity. The toxicity test of hydroethanolic extracts of M. annua and L. hastata species in mice established an LD50 indicates no toxicity. Conclusions: This study showed that, in addition to using medicinal plants for healing, the local population also uses them for other purposes. Keywords: Ethnobotany, Performance-enhancing plants, Phytochemistry, Safety, Burkina Faso

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Claims 6

Observationobservedoriginal resultmeasured

Claim · model-written summary

The survey identified 25 plant species from 17 families.

Taxon
plantsViridiplantaee0
Outcome
plants speciese0
Value
25e0
Setting
Bobo-Dioulassoe1

Verbatim

e0

“25 plants species belonging to 17 botanical families were identified.”

✓ located verbatim in the source · abstract, characters 701–770 · show in text ↑
e1

“medicinal plants used for doping in the city of Bobo-Dioulasso”

✓ located verbatim in the source · abstract, characters 193–255 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

Martynia annua, Securidaca longepedunculata and Leptadenia hastata were selected by citation frequency.

Taxon
Martynia annua LinMartynia annuae0
Outcome
selected for further studye0
Qualifier
frequency of citatione0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Martynia annua
Martynia annua · TaxonCarlos Domínguez-Rodríguez · CC BY 4.0 · iNaturalist ↗

Verbatim

e0

“Based on the frequency of citation, the species Martynia annua Lin (Martyniaceae), Securidaca longepedunculata Fresen (Polygalaceae), and Leptadenia hastata (Pesr.) Decne (Asclepiadaceae) were selected for further study.”

✓ located verbatim in the source · abstract, characters 771–991 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

Leaves were the most used plant part at 55.13%.

Taxon
medicinal plantse1
Organ / stage
leavese0
Outcome
most used partse0
Value
55.13%e0

Verbatim

e0

“The leaves (55.13%) and root bark (21.79%) were the most used parts.”

✓ located verbatim in the source · abstract, characters 992–1060 · show in text ↑
e1

“medicinal plants used for doping”

✓ located verbatim in the source · abstract, characters 193–225 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

Root bark accounted for 21.79% of used plant parts.

Taxon
medicinal plantse1
Organ / stage
root barke0
Outcome
most used partse0
Value
21.79%e0

Verbatim

e0

“The leaves (55.13%) and root bark (21.79%) were the most used parts.”

✓ located verbatim in the source · abstract, characters 992–1060 · show in text ↑
e1

“medicinal plants used for doping”

✓ located verbatim in the source · abstract, characters 193–225 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

Plant extracts contained polyphenols, flavonoids and tannins.

Taxon
medicinal plantse1
Outcome
presence of phenolic compounds such as polyphenols, total flavonoids and tanninse0

Verbatim

e0

“The phytochemical study revealed the presence of phenolic compounds such as polyphenols, total flavonoids and tannins.”

✓ located verbatim in the source · abstract, characters 1061–1179 · show in text ↑
e1

“medicinal plants used for doping”

✓ located verbatim in the source · abstract, characters 193–225 · show in text ↑
Observationobservedoriginal resultmeasured

Claim · model-written summary

Plant extracts showed antioxidant activity.

Taxon
medicinal plantse1
Outcome
antioxidant activitye0

Verbatim

e0

“The extracts exhibited antioxidant activity.”

✓ located verbatim in the source · abstract, characters 1180–1224 · show in text ↑
e1

“medicinal plants used for doping”

✓ located verbatim in the source · abstract, characters 193–225 · show in text ↑