Claim · model-written summary
A decrease in H perforatum intake from 5.7 to 2.85 g dry plant per kg live weight was associated with reduced severity of clinical signs.
- Taxon
- H perforatum
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Hypericum perforatume2 - Treatment
- H perforatum ingestione2
- Outcome
- severity of the clinical signse3
- Direction
- decreasee3
Verbatim
e2“A decrease in H perforatum ingestion from 5.7 to 2.85 g dry plant per kg live weight”
e3“was associated with a decrease in the severity of the clinical signs”
Title
CA BOURKE Australian Veterinary Journal 2000. doi:10.1111/j.1751-0813.2000.tb11868.x
Other claims from this paper (6)
- Intervention effect Hypericum perforatum ingestion followed by bright sunlight exposure caused clinical signs including an inappropriate increase in body temperature in sheep.
- Association Exposure to bright sunlight appears to be an absolute requirement before H perforatum effects develop.
- Observation A single dose of H perforatum remains potentially effective for up to 4 days.
- Observation The tolerance level for H perforatum eaten at the flowering stage was below 1% of body weight (plant wet weight) in the small Merino group tested.
- Observation The tolerance level for hypericin was below 2.65 mg per kg live weight in the small Merino group tested.
- Observation The rectal temperature rise in affected sheep is a reliable indicator of the early development of an adverse clinical effect.