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paper W7128909693 ✕

Observationobservedoriginal resultmeasured

Claim · model-written summary

Maize knobs exhibit a more structured HOR distribution than centromeres.

Taxon
maizeZea mayse0
Outcome
more structured HOR distributione0

Verbatim

e0

“maize knobs exhibit a more structured HOR distribution”

✓ located verbatim in the source · abstract, characters 1258–1312

Title

Higher order repeat structures reflect diverging evolutionary paths in maize centromeres and knobs

Rebecca D. Piri; Mingyu Wang; M. Cinta Romay; et al. Genome biology 2026. doi:10.1186/s13059-026-03993-4

Other claims from this paper (9)
Observationobservedoriginal resultmeasured

Claim · model-written summary

Large maize knobs contain megabase-scale similarity blocks with repeated HOR patterns.

Taxon
maizeZea mayst0
Outcome
megabase-scale similarity blocks with repeated HOR patternse0

Verbatim

t0

“maize”

✓ located verbatim in the source · title, characters 71–76
e0

“Large knobs contain megabase-scale similarity blocks with repeated HOR patterns”

✓ located verbatim in the source · abstract, characters 1314–1393

Title

Higher order repeat structures reflect diverging evolutionary paths in maize centromeres and knobs

Rebecca D. Piri; Mingyu Wang; M. Cinta Romay; et al. Genome biology 2026. doi:10.1186/s13059-026-03993-4

Other claims from this paper (9)
Mechanismhypothesisoriginal resultmeasured

Claim · model-written summary

The repeat units in knobs likely promote unequal crossing over, enabling rapid knob expansion.

Taxon
maizeZea mayst0
Outcome
rapid knob expansione0
Qualifier
unequal crossing overe0

Verbatim

t0

“maize”

✓ located verbatim in the source · title, characters 71–76
e0

“These repeat units likely promote unequal crossing over, enabling rapid knob expansion”

✓ located verbatim in the source · abstract, characters 1395–1481

Title

Higher order repeat structures reflect diverging evolutionary paths in maize centromeres and knobs

Rebecca D. Piri; Mingyu Wang; M. Cinta Romay; et al. Genome biology 2026. doi:10.1186/s13059-026-03993-4

Other claims from this paper (9)
Observationobservedoriginal resultmeasured

Claim · model-written summary

Arabidopsis centromeres have a similar HOR landscape to maize centromeres.

Taxon
ArabidopsisArabidopsise0
Outcome
similar HOR landscapee0

Verbatim

e0

“Arabidopsis centromeres have a similar HOR landscape”

✓ located verbatim in the source · abstract, characters 1191–1243

Title

Higher order repeat structures reflect diverging evolutionary paths in maize centromeres and knobs

Rebecca D. Piri; Mingyu Wang; M. Cinta Romay; et al. Genome biology 2026. doi:10.1186/s13059-026-03993-4

Other claims from this paper (9)
Observationobservedoriginal resultmeasured

Claim · model-written summary

About 38% of centromeric CentC monomers in maize occur in higher-order repeats.

Taxon
maizeZea mayst0
Outcome
centromeric CentC monomers occur in HORse0
Value
38%e0

Verbatim

t0

“maize”

✓ located verbatim in the source · title, characters 71–76
e0

“Approximately 38% of centromeric CentC monomers occur in HORs”

✓ located verbatim in the source · abstract, characters 1024–1085

Title

Higher order repeat structures reflect diverging evolutionary paths in maize centromeres and knobs

Rebecca D. Piri; Mingyu Wang; M. Cinta Romay; et al. Genome biology 2026. doi:10.1186/s13059-026-03993-4

Other claims from this paper (9)
Observationobservedoriginal resultmeasured

Claim · model-written summary

No specific HOR class dominates any functional centromere (marked by centromeric histone H3) in maize.

Taxon
maizeZea mayst0
Outcome
no specific HOR class dominates any functional centromeree0

Verbatim

t0

“maize”

✓ located verbatim in the source · title, characters 71–76
e0

“no specific HOR class dominates any functional centromere”

✓ located verbatim in the source · abstract, characters 1096–1153

Title

Higher order repeat structures reflect diverging evolutionary paths in maize centromeres and knobs

Rebecca D. Piri; Mingyu Wang; M. Cinta Romay; et al. Genome biology 2026. doi:10.1186/s13059-026-03993-4

Other claims from this paper (9)
Method / resourceobservedoriginal resultbasis n/a

Claim · model-written summary

Thirteen repeat-sensitive genome assemblies of maize and its recent ancestor teosinte were generated.

Taxon
maizeZea mayse0
Outcome
repeat-sensitive genome assembliese0
Value
13e0

Verbatim

t0

“maize”

✓ located verbatim in the source · title, characters 71–76
e0

“we generate 13 repeat-sensitive genome assemblies of maize and its recent ancestor, teosinte”

✓ located verbatim in the source · abstract, characters 623–715

Title

Higher order repeat structures reflect diverging evolutionary paths in maize centromeres and knobs

Rebecca D. Piri; Mingyu Wang; M. Cinta Romay; et al. Genome biology 2026. doi:10.1186/s13059-026-03993-4

Other claims from this paper (9)
Mechanismhypothesisoriginal resultmeasured

Claim · model-written summary

The repeat units may harbor motifs recognized by trans-acting factors involved in meiotic drive.

Taxon
maizeZea mayst0
Outcome
meiotic drivee0
Qualifier
motifs recognized by trans-acting factorse0

Verbatim

t0

“maize”

✓ located verbatim in the source · title, characters 71–76
e0

“may harbor motifs recognized by trans-acting factors involved in meiotic drive”

✓ located verbatim in the source · abstract, characters 1487–1565

Title

Higher order repeat structures reflect diverging evolutionary paths in maize centromeres and knobs

Rebecca D. Piri; Mingyu Wang; M. Cinta Romay; et al. Genome biology 2026. doi:10.1186/s13059-026-03993-4

Other claims from this paper (9)
Observationobservedoriginal resultmeasured

Claim · model-written summary

Higher-order repeats are ubiquitous in maize satellites but are typically low-frequency with small patterns.

Taxon
maizeZea mayse0
Outcome
HORs are ubiquitous in maize satellitese0
Qualifier
low-frequency with small patternse0

Verbatim

e0

“HORs are ubiquitous in maize satellites but are typically low-frequency with small patterns”

✓ located verbatim in the source · abstract, characters 854–945

Title

Higher order repeat structures reflect diverging evolutionary paths in maize centromeres and knobs

Rebecca D. Piri; Mingyu Wang; M. Cinta Romay; et al. Genome biology 2026. doi:10.1186/s13059-026-03993-4

Other claims from this paper (9)
Method / resourceobservedoriginal resultpositivebasis n/a

Claim · model-written summary

A new graph-based pipeline, HiReNET, was developed to classify higher-order repeats and was shown to work in Arabidopsis and maize.

Taxon
Arabidopsis and maizeArabidopsisZea mayse0
Outcome
classify HORse0

Not reportedComparator

Verbatim

e0

“We develop a new graph-based pipeline, HiReNET, to classify HORs and demonstrate its utility in both Arabidopsis and maize”

✓ located verbatim in the source · abstract, characters 717–839

Title

Higher order repeat structures reflect diverging evolutionary paths in maize centromeres and knobs

Rebecca D. Piri; Mingyu Wang; M. Cinta Romay; et al. Genome biology 2026. doi:10.1186/s13059-026-03993-4

Other claims from this paper (9)

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