Claim · model-written summary
When DNA repair polymerases alpha and beta are inhibited by aphidicolin and dideoxythymidine triphosphate, gamma-irradiation-induced DNA fragmentation cannot be fully repaired.
- Taxon
- rye ( Secale cereale ) and wild oat ( Avena fatua )
Avena fatua
Secale cerealee1 - Treatment
- aphidicolin and dideoxythymidine-5'-triphosphatee0
- Outcome
- DNA fragmentatione0
Not reportedMaterialGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleComparatorSettingDirectionValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“when α- and β-polymerases of DNA repair are inhibited by aphidicolin and dideoxythymidine-5'-triphosphate, respectively, a γ-irradiation-induced DNA fragmentation cannot be fully repaired”
e1“rye ( Secale cereale ) and wild oat ( Avena fatua )”
Title
The requirement for DNA repair in desiccation tolerance of germinating embryos
Ivan Boubriak; Haroula Kargiolaki; Linden Lyne; et al. Seed Science Research 1997. doi:10.1017/s0960258500003433
Other claims from this paper (5)
- Mechanism The authors propose that desiccation tolerance of the seed embryo depends on its capacity to repair damage to genomic DNA when rehydrated.
- Observation In imbibed and hydrated rye and wild oat embryos, neither the extent of water uptake, the stability of the DNA to desiccation, nor the onset of S-phase DNA synthesis determines whether the desiccated embryo survives.
- Observation In hydrated embryos at a stage when desiccation tolerance is lost, embryo cells still repair irradiation-induced DNA damage.
- Observation In hydrated embryos at the stage when desiccation tolerance is lost, the repaired DNA is unstable to desiccation and cannot be rerepaired when water is again made available.
- Mechanism The failure to re-repair DNA on rehydration appears to be critical to embryo survival and successful germination.