Claim · model-written summary
Caspase inhibitors suppressed DNA fragmentation and cell death.
- Taxon
- Arabidopsis
Arabidopsist0 - Treatment
- caspase1, caspase-3 inhibitors and the pancaspase inhibitor p35e0
- Outcome
- DNA fragmentation and cell deathe0
- Direction
- suppresse0
Not reportedMaterialGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleComparatorSettingValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“caspase1, caspase-3 inhibitors and the pancaspase inhibitor p35 were able to suppress DNA fragmentation and cell death”
t0“Arabidopsis”
Title
Caspase-like activities and UV-induced programmed cell death in Arabidopsis
V Rotari; A Gordon; R He; et al. BMC Plant Biology 2005. doi:10.1186/1471-2229-5-s1-s18
Other claims from this paper (5)
- Intervention effect UV induced apoptotic-like cellular changes.
- Mechanism UV-induced PCD required light.
- Observation DEVDase activity was induced within 30 minutes and peaked at one hour.
- Intervention effect DEVDase was insensitive to broad-range cysteine protease inhibitors.
- Mechanism YVADase and DEVDase may mediate DNA fragmentation under UV overexposure.