Intervention effectmodel-written summary

TaBZR2 RNAi decreased wheat resistance to multiple Pst races.

A claim from Transcription factor BZR2 activates chitinase Cht20.2 transcription to confer resistance to wheat stripe rust · 2021

Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

Taxon: WheatTriticum aestivume0
Treatment: TaBZR2-RNAie0
Interactor: Pste1pathogen
Gene: TaBZR2e0
Outcome: resistance to multiple races of Pste0
Direction: decreasede0

Not reportedMaterialCompoundOrgan / stageSecond interactorSecond interactor roleComparatorSettingValueQualifier

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

*Triticum aestivum* · TaxonRasbak · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0
“Wheat lines overexpressing TaBZR2 conferred increased resistance, whereas TaBZR2-RNAi lines exhibited decreased resistance to multiple races of Pst”
✓ located verbatim in the source · abstract, characters 772–919

e1
“Puccinia striiformis f. sp. tritici, Pst”
✓ located verbatim in the source · abstract, characters 661–701

Title

Transcription factor BZR2 activates chitinase Cht20.2 transcription to confer resistance to wheat stripe rust

Xingxuan Bai; Gangming Zhan; Shuxin Tian; et al. PLANT PHYSIOLOGY 2021. doi:10.1093/plphys/kiab383

Other claims from this paper (8)

Intervention effect Pst inoculation upregulated TaBZR2 transcripts in wheat.
Intervention effect Flg22 treatment upregulated TaBZR2 transcripts in wheat.
Intervention effect Pst322 treatment upregulated TaBZR2 transcripts in wheat.
Intervention effect TaBZR2 overexpression increased wheat resistance to multiple Pst races.
Mechanism TaBZR2 targeted the TaCht20.2 promoter and activated its transcription.
Intervention effect TaCht20.2 knockdown enhanced wheat susceptibility to Pst.
Intervention effect TaBZR2 overexpression increased total chitinase activity after Pst infection.
Intervention effect TaBZR2 silencing reduced total chitinase activity after Pst infection.

Record rev-2f7161a8339cc0ca32752037eb750b3f21af4c6456971204c24992f1a1e8339f · schema claims-v0.9 · position 5 in the model’s answer

Functional evidence on TaBZR2

Claims that state a gain or loss of function of this gene and what it did to a trait, compared with wild type or a control.

TaBZR2 · Open in the knowledge graph

Triticum aestivum (wheat)2 papers · 2 traits

Disease resistance1 paper

Promotes
TaBZR2 overexpression increased wheat resistance to multiple Pst races.
Transcription factor BZR2 activates chitinase Cht20.2 transcription to confer resistance to wheat stripe rust · 2021
gain of function → more of the trait
Promotes
TaBZR2 RNAi decreased wheat resistance to multiple Pst races.
Transcription factor BZR2 activates chitinase Cht20.2 transcription to confer resistance to wheat stripe rust · 2021
loss of function → less of the traitThis claim

Heat tolerance1 paper

Promotes
Overexpression of TaBZR2 enhanced heat stress tolerance in wheat.
Somatic embryogenetic receptor kinase TaSERL2 regulates heat stress tolerance in wheat by influencing TaBZR2 protein stability and transcriptional activity · 2025
gain of function → more of the trait

The program reads each claim's manipulation and the direction of the trait, and from them the gene's role (gain and more, or loss and less, means it promotes the trait). Roles are read by program from each claim's wording. Pairs of papers on the same host, gene and trait were checked claim by claim by two model readers; a pair is marked checked only when both accept it. Gene layer v0.8, 21 trait classes.