Claim · model-written summary
The TRKIN/TR-1 system probably facilitates the meiotic drive of the KINDR/knob180 system.
Zea maysNot reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingDirectionValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Distinct kinesin motors drive two types of maize neocentromeres”
e5“suggests that the current role of the TRKIN/TR-1 system is to facilitate the meiotic drive of the KINDR/knob180 system”
Title
Distinct kinesin motors drive two types of maize neocentromeres
Kyle W. Swentowsky; Jonathan I. Gent; Elizabeth G. Lowry; et al. Genes & Development 2020. doi:10.1101/gad.340679.120
Other claims from this paper (6)
- Observation Trkin encodes a functional minus end-directed kinesin that colocalizes with TR-1 in meiosis.
- Observation Trkin is required to mobilize neocentromeres made up of the minor tandem repeat TR-1.
- Observation Trkin shows extraordinary sequence divergence from Kindr and other plant kinesins.
- Observation The Trkin region of Ab10 is not syntenic with any other region of the maize genome.
- Association TRKIN localizes to knobs earlier in prophase than KINDR.
- Observation TRKIN contains a nuclear localization signal.