Claim · model-written summary
Compound I formation rate constants with peroxobenzoic acids declined as pH rose.
- Taxon
- horseradish
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Armoracia rusticanat0 - Gene
- horseradish peroxidaset0
- Outcome
- second-order rate constants for the formation of Compound Ie0
- Direction
- decreasee0
- Qualifier
- pH 5-10e0
Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingValue
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
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Verbatim
e0“The observed second-order rate constants for the formation of Compound I with peroxobenzoic acids decrease with increasing pH, in the range pH 5-10”
t0“horseradish peroxidase”
Title
D M Davies; P Jones; D Mantle Biochemical Journal 1976. doi:10.1042/bj1570247
Other claims from this paper (7)
- Association Compound I formation with H2O2 was independent of pH.
- Observation Maximal Compound I formation rates with unhindered peroxobenzoic acids exceeded the H2O2 rate.
- Observation Bulky ortho substituents of peroxobenzoic acids had adverse steric effects.
- Observation Substituent effect patterns disagreed with an electrophilic oxidation expectation.
- Observation Substituent effect patterns agreed with expected nucleophilic attack by peroxo anions.
- Mechanism The authors infer Compound I forms through reaction with un-ionized hydroperoxide molecules.
- Mechanism The authors propose an electrostatic gate model to explain pH and substituent effects.