Claim · model-written summary
An arginine-to-isoleucine missense mutation in a proposed linker domain caused loss of function.
- Taxon
- Pea
Lathyrus oleraceust0 - Gene
- argininee0
- Outcome
- loss-of-functione0
- Qualifier
- domain proposed to link the predicted channel and the gating ring domainse0
Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingDirectionValue
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Pea SYM8 Symbiosis Gene”
e0“a loss-of-function missense mutation (changing arginine to isoleucine) in a domain proposed to link the predicted channel and the gating ring domains”
Title
Anne Edwards; Anne B. Heckmann; Faridoon Yousafzai; et al. Molecular Plant-Microbe Interactions 2007. doi:10.1094/mpmi-20-10-1183
Other claims from this paper (10)
- Intervention effect Mutation of sym8 in R25 blocks nodulation, mycorrhization, and Nod-factor-induced calcium spiking.
- Observation Four new pea sym8 alleles belong to the same complementation group as R25.
- Observation Pea sym8 mutants phenotypically resemble Medicago truncatula dmi1 mutants.
- Observation Pea sym8 mutants map to a syntenic location.
- Intervention effect The cloned pea DMI1 ortholog complements a Medicago truncatula dmi1 mutant for nodulation.
- Observation All five pea sym8 mutants carry mutations in the DMI1 ortholog.
- Observation The pea SYM8 gene is the DMI1 ortholog.
- Observation A predicted SYM8 channel structure has four aspartate residues forming its opening.
- Intervention effect Aspartate-to-valine mutation in the predicted filter region caused loss of function.
- Intervention effect An alanine-to-valine missense mutation in the predicted filter region caused loss of function.