Claim · model-written summary
Compound 5 showed a significant antimicrobial effect against Haemophilus influenzae, with a MIC of 7.81 μg/mL.
- Taxon
- Tabernaemontana inconspicuaTabernaemontana inconspicuae0
- Interactor
- Haemophilus influenzae
Haemophilus influenzaee1pathogen - Outcome
- minimum inhibitory concentrations (MIC)e1
- Value
- 7.81 μg/mLe1
Not reportedMaterialGeneCompoundOrgan / stageSecond interactorSecond interactor roleTreatmentComparatorSettingDirectionQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“A chemical investigation of the leaves of Tabernaemontana inconspicua Stapf.”
e1“Compounds 1, 3, and 5 showed significant antimicrobial effects with minimum inhibitory concentrations (MIC) of 62.5 μg/mL, 62.5 μg/mL and 7.81 μg/mL, respectively, against Haemophilus influenzae”
Title
Lidwine Ngah; Willifred Dongmo Tékapi Tsopgni; Judith Caroline Ngo Nyobe; et al. Antibiotics 2022. doi:10.3390/antibiotics11010121
Other claims from this paper (7)
- Observation A new phenylpropanol derivative, irisdichototin G, was isolated from the leaves of Tabernaemontana inconspicua.
- Observation Dambonitol (compound 2) was reported for the first time from the family Apocynaceae.
- Observation Compound 1 showed a significant antimicrobial effect against Haemophilus influenzae, with a MIC of 62.5 μg/mL.
- Observation Compound 3 showed a significant antimicrobial effect against Haemophilus influenzae, with a MIC of 62.5 μg/mL.
- Observation Compounds 1 and 5 showed a significant antimicrobial effect against Pseudomonas aeruginosa, with a MIC of 31.25 μg/mL.
- Observation Compound 3 showed a significant antimicrobial effect against Klebsiella pneumoniae, with a MIC of 31.25 μg/mL.
- Observation Nine known compounds were isolated together with the new compound from Tabernaemontana inconspicua leaves.