Intervention effectmodel-written summary

Calcium chelation suppressed iron dependent ROS accumulation and ferroptotic death.

A claim from Cytoplasmic Ca2+ influx mediates iron- and reactive oxygen species-dependent ferroptotic cell death in rice immunity · 2024

Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

Calcium chelation suppressed iron dependent ROS accumulation and ferroptotic death.

Treatment
Ca 2+ chelatione0
Outcome
Ca 2+ -mediated iron-dependent ROS accumulation and ferroptotic cell deathe0
Direction
suppressede0

Not reportedMaterialGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleComparatorSettingValueQualifier

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Oryza sativa
Oryza sativa · Taxon · picture from its Wikimedia Commons categoryDesmanthus4food · CC BY-SA 3.0 us · Wikimedia Commons ↗

Verbatim

e0

“Blocking apoplastic Ca 2+ influx into the cytoplasm by Ca 2+ chelation effectively suppressed Ca 2+ -mediated iron-dependent ROS accumulation and ferroptotic cell death.”

✓ located verbatim in the source · abstract, characters 982–1151
t0

“Cytoplasmic Ca2+ influx mediates iron- and reactive oxygen species-dependent ferroptotic cell death in rice immunity”

✓ located verbatim in the source · title, characters 0–116

Title

Cytoplasmic Ca2+ influx mediates iron- and reactive oxygen species-dependent ferroptotic cell death in rice immunity

Juan Wang; Won-Gyu Choi; Nam Khoa Nguyen; et al. Frontiers in Plant Science 2024. doi:10.3389/fpls.2024.1339559

Other claims from this paper (5)

Record rev-4f10cba09ea2c69fd23c23c5b4987095932fd53480ef35fdf0799655fd8de914 · schema claims-v0.9 · position 5 in the model’s answer

calcium(2+) · physiology: oxidative · Oryza sativa (rice)Positive and negative results

3 papers: 2 positive, 1 negative or no effect

2 in the opposite direction

  1. positive
    Added calcium decreased electrolyte leakage and MDA content in chilled seedlings.

    The Protective Function of Ca~(2+) on the Membrane of Rice Seedling under Low Temperature Stress · 2001

    Opposite direction

  2. positive
    At 10 mmol/L Ca2+, H2O2 and MDA contents were lower than at 5 mmol/L under nickel stress.

    Effects of External Calcium on Activities of Antioxidant Enzymes and Membrane Lipid Peroxidation in Rice Seedlings under Nickel Stress · 2007 · compared with 5 mmol/L Ca2+

    Opposite direction

See all 3 papers →

Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.