Claim · model-written summary
Treatment for 90 days caused significantly higher mortality than controls.
- Taxon
- laboratory animalse1
- Treatment
- prolong treatment (90 days)e0
- Outcome
- mortalitye0
- Direction
- highere0
- Comparator
- control groupe0
Not reportedMaterialGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleSettingValueQualifier
Verbatim
e0“However, prolong treatment (90 days) causes significantly higher mortality as compared to control group.”
e1“The ethanol extract of the plant was tested on laboratory animals”
Title
Pharmacological Studies on Aerial Parts of Calotropis Procera
J. S. Mossa; M. Tariq; A. Mohsin; et al. The American Journal of Chinese Medicine 1991. doi:10.1142/s0192415x91000302
Other claims from this paper (6)
- Intervention effect Calotropis extract had significant antipyretic, analgesic and neuromuscular blocking activity in laboratory animals.
- Intervention effect The extract produced guinea pig ileum contractions blocked by atropine.
- Intervention effect The extract did not produce significant anti-inflammatory or antibacterial activity.
- Observation C. procera aerial parts contained alkaloids, cardiac glycosides and tannins.
- Observation C. procera aerial parts contained flavonoids and sterols and/or triterpenes.
- Intervention effect Single extract doses up to 3 g/kg produced no visible toxic symptoms or mortality.