Intervention effectmodel-written summary

Overexpression of CmWRKY22 inhibited CMV infection in C. maxima.

A claim from Genome-Wide Identification and Characterization of the WRKY Gene Family in Cucurbita maxima · 2023

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Overexpression of CmWRKY22 inhibited CMV infection in C. maxima.

Taxon: Cucurbita maximaCucurbita maximat0
Treatment: overexpression of CmWRKY22e0
Interactor: CMVcucumber mosaic cucumoviruse0pathogen
Gene: CmWRKY22e0
Outcome: CMV infectione0
Direction: inhibitede0

Not reportedMaterialCompoundOrgan / stageSecond interactorSecond interactor roleComparatorSettingValueQualifier

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

*Cucurbita maxima* · Taxonmikami-kun · CC BY 4.0 · iNaturalist ↗

*cucumber mosaic cucumovirus* · InteractorDieterO · Public domain · Wikimedia Commons ↗

Verbatim

e0
“overexpression of CmWRKY22 inhibited the CMV infection”
✓ located verbatim in the source · abstract, characters 620–674

t0
“Cucurbita maxima”
✓ located verbatim in the source · title, characters 75–91

Title

Genome-Wide Identification and Characterization of the WRKY Gene Family in Cucurbita maxima

Qin Zhou; Ziqing Guo; Xiaojun Zhou; et al. Genes 2023. doi:10.3390/genes14112030

Other claims from this paper (3)

Observation The C. maxima genome contained 102 identified CmWRKY genes.
Intervention effect Silencing CmWRKY22 promoted CMV infection in C. maxima.
Observation CmWRKY22 bound the W-box at the CmPR1b promoter.

Record rev-6632d285127ffab298b0610fb8460d0f8a0e5aab31b1511f432ef85917d02552 · schema claims-v0.9 · position 3 in the model’s answer

Functional evidence on CmWRKY22

Claims that state a gain or loss of function of this gene and what it did to a trait, compared with wild type or a control.

CmWRKY22

Cucurbita maxima (winter squash)1 paper · 1 traitTested in one paper only

Only one paper in the store tests this gene's function in Cucurbita maxima (winter squash).

Disease resistance1 paper

Promotes
Silencing CmWRKY22 promoted CMV infection in C. maxima.
Genome-Wide Identification and Characterization of the WRKY Gene Family in Cucurbita maxima · 2023
loss of function → less of the trait
Promotes
Overexpression of CmWRKY22 inhibited CMV infection in C. maxima.
Genome-Wide Identification and Characterization of the WRKY Gene Family in Cucurbita maxima · 2023
gain of function → more of the traitThis claim

The program reads each claim's manipulation and the direction of the trait, and from them the gene's role (gain and more, or loss and less, means it promotes the trait). Roles are read by program from each claim's wording. Pairs of papers on the same host, gene and trait were checked claim by claim by two model readers; a pair is marked checked only when both accept it. Gene layer v0.8, 21 trait classes.