Intervention effectmodel-written summary

Overexpression of TaSERL2 reduced heat stress tolerance in wheat.

A claim from Somatic embryogenetic receptor kinase TaSERL2 regulates heat stress tolerance in wheat by influencing TaBZR2 protein stability and transcriptional activity · 2025

Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

Taxon: wheatTriticum aestivumt0
Treatment: Overexpression of TaSERL2e5
Gene: TaSERL2e5
Outcome: heat stress tolerancee5
Direction: reducede5

Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleComparatorSettingValueQualifier

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

*Triticum aestivum* · TaxonRasbak · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

t0
“regulates heat stress tolerance in wheat”
✓ located verbatim in the source · title, characters 46–86

e5
“Overexpression of TaSERL2 reduced heat stress tolerance by promoting TaBZR2 degradation and inhibiting its regulation of wheat heat stress response genes”
✓ located verbatim in the source · abstract, characters 748–901

Title

Somatic embryogenetic receptor kinase TaSERL2 regulates heat stress tolerance in wheat by influencing TaBZR2 protein stability and transcriptional activity

Xiang‐Yang Hao; Tai‐Fei Yu; Chao‐Jun Peng; et al. Plant Biotechnology Journal 2025. doi:10.1111/pbi.70045

Other claims from this paper (9)

Association TaBZR2 expression was strongly positively correlated with heat stress tolerance in wheat.
Intervention effect Overexpression of TaBZR2 enhanced heat stress tolerance in wheat.
Intervention effect RNA interference of TaBZR2 reduced heat stress tolerance in wheat.
Observation TaBZR2 interacts with and is phosphorylated by TaSERL2 in wheat.
Mechanism TaSERL2 promotes degradation of TaBZR2 in wheat.
Mechanism TaSERL2 inhibits the regulation of wheat heat stress response genes by TaBZR2.
Intervention effect Heat stress reduced the phosphorylation levels of both TaSERL2 and TaBZR2 in wheat.
Intervention effect Heat stress enhanced the stability of TaBZR2 in wheat by lessening TaSERL2 inhibition.
Mechanism The TaSERL2-TaBZR2 module negatively regulates heat stress tolerance in wheat.

Record rev-7a0dbc448e6bc727b1716cc7865e8bc5fdd69862158213a32b3679844c0e586a · schema claims-v0.9 · position 5 in the model’s answer

Functional evidence on TaSERL2

Claims that state a gain or loss of function of this gene and what it did to a trait, compared with wild type or a control.

TaSERL2

Triticum aestivum (wheat)1 paper · 1 traitTested in one paper only

Only one paper in the store tests this gene's function in Triticum aestivum (wheat).

Heat tolerance1 paper

Restrains
Overexpression of TaSERL2 reduced heat stress tolerance in wheat.
Somatic embryogenetic receptor kinase TaSERL2 regulates heat stress tolerance in wheat by influencing TaBZR2 protein stability and transcriptional activity · 2025
gain of function → less of the traitThis claim

The program reads each claim's manipulation and the direction of the trait, and from them the gene's role (gain and more, or loss and less, means it promotes the trait). Roles are read by program from each claim's wording. Pairs of papers on the same host, gene and trait were checked claim by claim by two model readers; a pair is marked checked only when both accept it. Gene layer v0.8, 21 trait classes.