Claim · model-written summary
The pmr4-1 mutation blocked pathogen entry from epidermal cells to the stele in a jasmonic acid signaling-dependent manner in Arabidopsis.
- Taxon
- Arabidopsis
Arabidopsise6 - Material
- pmr4-1e6
- Organ / stage
- epidermal cellse6
- Treatment
- pmr4-1 mutatione6
- Interactor
- P. brassicae
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Plasmodiophora brassicaee6pathogen - Outcome
- pathogen entry from epidermal cells to the stelee6
- Qualifier
- jasmonic acid signaling-dependent mannere6
Not reportedGeneCompoundSecond interactorSecond interactor roleComparatorSettingDirectionValue
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
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Verbatim
e6“The Arabidopsis pmr4-1 mutation does not affect P. brassicae primary infection but blocks the pathogen entry from epidermal cells to the stele in a jasmonic acid signaling-dependent manner”
Title
Runbang Luo; Lipu Wang; Rui Wen; et al. The Plant Cell 2026. doi:10.1093/plcell/koag160
Other claims from this paper (9)
- Intervention effect Recessive PMR4 mutations in Arabidopsis conferred strong resistance to multiple Plasmodiophora brassicae pathotypes.
- Intervention effect Homozygous CRISPR-edited PMR4 orthologs in Brassica napus conferred resistance to powdery mildew and clubroot.
- Intervention effect Plasmodiophora brassicae infection induced callose deposition in Arabidopsis roots in a PMR4-dependent manner.
- Intervention effect Plasmodiophora brassicae infection induced callose deposition in Brassica napus roots in a PMR4-dependent manner.
- Intervention effect The pmr4-1 mutation did not affect primary infection by Plasmodiophora brassicae in Arabidopsis.
- Association Blocked pathogen entry in pmr4-1 coincided with accumulation of lignin-like and suberin compounds in periderm cell walls of Arabidopsis.
- Mechanism PMR4-encoded callose synthase is a host susceptibility factor facilitating secondary infection by Plasmodiophora brassicae.
- Recommendation PMR4 is a gene-editing target for enhancing resistance to powdery mildew and clubroot in Brassicaceae crops.
- Observation PMR4 was identified as a potential host susceptibility factor in Arabidopsis and Brassica napus.