Claim · model-written summary
P. infestans culture filtrate releases StNTP1 and StNTP2 from the ER and they accumulate in the nucleus.
- Taxon
- potato
Solanum tuberosumt0 - Treatment
- P. infestans CFe0
- Interactor
- P. infestans
Phytophthora infestanse0pathogen - Gene
- StNTP1 and StNTP2e0
- Outcome
- StNTP1 and StNTP2 proteinse0
- Direction
- accumulatee0
Not reportedMaterialCompoundOrgan / stageSecond interactorSecond interactor roleComparatorSettingValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“StNTP1 and StNTP2 proteins are released from the ER membrane following treatment with P. infestans CF and accumulate in the nucleus”
t0“The potato late blight pathogen Phytophthora infestans”
Title
Hazel McLellan; Petra C. Boevink; Miles R. Armstrong; et al. PLoS Pathogens 2013. doi:10.1371/journal.ppat.1003670
Other claims from this paper (14)
- Observation Two putative membrane-associated NAC transcription factors were identified as Pi03192 host targets.
- Observation Pi03192 interacts with NTP1 and NTP2 at the ER membrane.
- Intervention effect NTP1 and NTP2 transcripts rapidly accumulate after P. infestans culture filtrate treatment.
- Association NTP1 and NTP2 transcripts significantly decrease during P. infestans infection.
- Intervention effect Silencing NTP1 in Nicotiana benthamiana increases susceptibility to P. infestans.
- Intervention effect Silencing NTP2 in Nicotiana benthamiana increases susceptibility to P. infestans.
- Intervention effect Silencing Pi03192 in P. infestans reduces its pathogenicity.
- Intervention effect Transient Pi03192 expression in plants restores pathogenicity of the Pi03192-silenced line.
- Intervention effect NTP1-silenced Nicotiana plants enhance colonisation by the Pi03192-silenced line.
- Intervention effect NTP2-silenced Nicotiana plants enhance colonisation by the Pi03192-silenced line.
- Observation The 26S proteasome rapidly turns over StNTP1 and StNTP2 after nuclear accumulation.
- Intervention effect Flg22 fails to up-regulate NTP1 and NTP2.
- Intervention effect Flg22 fails to relocate NTP1 and NTP2 protein products to the nucleus.
- Intervention effect Pi03192 prevents culture filtrate-triggered relocation of StNTP1 and StNTP2 into the nucleus.