Claim · model-written summary
The study deciphered a kinase-centered network related to BR-regulated growth.
- Taxon
- Arabidopsis
Arabidopsist0 - Outcome
- kinase-centered network related to BR-regulated growthe0
Not reportedMaterialGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingDirectionValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“a complicated kinase-centered network related to BR-regulated growth was deciphered.”
t0“Arabidopsis”
Title
Li-Ling Lin; Chia-Lang Hsu; Chia-Wei Hu; et al. BMC Genomics 2015. doi:10.1186/s12864-015-1753-4
Other claims from this paper (12)
- Method / resource The phosphoproteome analysis identified 1104 phosphorylated peptides from 739 phosphoproteins.
- Observation The same analysis identified 739 unique phosphoproteins.
- Observation Time-dependent GO analysis showed a shift from signaling transduction to morphogenesis and stress response.
- Association Most identified phosphoproteins were strongly connected to known BR signaling components.
- Method / resource Motif-X identified 15 enriched motifs.
- Observation Eleven enriched motifs corresponded to six known kinase families.
- Intervention effect Casein kinase 2 substrates were significantly phosphorylated at the start of BR treatment.
- Intervention effect Mitogen-activated protein kinase substrates were significantly dephosphorylated at the start of BR treatment.
- Observation Time-dependent kinase-substrate networks indicated many substrates downstream of auxin and ABA signals.
- Association Most BR-responsive phosphorylation changes were not driven by gene expression changes.
- Mechanism The authors interpret downstream BR signaling proteins as being induced by kinase phosphorylation rather than transcriptional regulation.
- Observation The identified phosphoproteins and phosphosites provide a dataset for BR signaling studies.