Claim · model-written summary
The mixture of compounds 3 and 4 gave an IC50 of 1333 nM
- Taxon
- Zanthoxylum gilletiiZanthoxylum gilletiit0
- Compound
- mixture of 3 + 4e4
- Outcome
- IC50e4
- Value
- IC50 = 1333 nMe4
Not reportedMaterialGeneOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingDirectionQualifier
Verbatim
t0“Chemical Constituents of the Bark of Zanthoxylum gilletii (Rutaceae)”
e4“only the mixture of 3 + 4 gave an IC50 lower than 10 000 nM (IC50 = 1333 nM)”
Title
Liliane Clotilde Dzouemo; Gervais Mouthé Happi; Sikiru Akinyeye Ahmed; et al. Journal of Chemistry 2022. doi:10.1155/2022/1111817
Other claims from this paper (4)
- Observation Thirteen compounds were isolated from the bark of Zanthoxylum gilletii
- Observation Tested compounds showed 51.89% to 54.69% inhibition of Plasmodium falciparum 3D7 in vitro
- Observation Sesamin showed greater in silico affinity to the antiplasmodial target than artemether and chloroquine
- Observation Most isolated compounds are reported for the first time from Zanthoxylum gilletii