Claim · model-written summary
Simulated MYC2 activation was among the best single-node interventions for drought-responsive reporter genes.
- Taxon
- Arabidopsis
Arabidopsise1 - Treatment
- activating MYC2e0
- Gene
- MYC2e0
- Outcome
- drought-responsive reporter genese0
- Value
- best single node intervention strategiese0
Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleComparatorSettingDirectionQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“activating MYC2 or inhibiting ATAF1 are the best single node intervention strategies to regulate the drought-responsive reporter genes”
e1“drought signaling pathways in Arabidopsis”
Title
Detecting drought regulators using stochastic inference in Bayesian networks
Aditya Lahiri; Lin Zhou; Ping He; et al. PLoS ONE 2021. doi:10.1371/journal.pone.0255486
Other claims from this paper (4)
- Method / resource Simulated ATAF1 inhibition was among the best single-node interventions for drought-responsive reporter genes.
- Method / resource Combined MYC2 activation and ATAF1 inhibition performed better than single-node interventions.
- Method / resource The Bayesian model identified MYC2 and ATAF1 as possible drought response regulators.
- Mechanism Validation experiments found ATAF1 negatively regulated drought response.