Claim · model-written summary
The oils had MMC 0.26-10.19 mg/mL against Staphylococcus aureus.
- Taxon
- Staphylococcus aureus
Staphylococcus aureuse0 - Outcome
- MMCe0
- Value
- 0.26-10.19 mg/mLe0
Not reportedMaterialGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingDirectionQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Staphylococcus aureus (MIC = 0.004 mg/mL and MMC = 0.26-10.19 mg/mL)”
Title
Fabrício Souza Silva; Pedro Modesto Nascimento Menezes; Pedro Guilherme Souza de Sá; et al. Pharmaceutical Biology 2015. doi:10.3109/13880209.2015.1005751
Other claims from this paper (14)
- Observation Leaf oils contain beta-caryophyllene as the major constituent at 17.22-26.27%.
- Observation Leaf oils contain borneol at 4.45-7.36%.
- Observation Leaf oils contain camphor at 3.22-8.61%.
- Observation Leaf oils contain camphene at 2.64-5.66%.
- Observation Leaf oils contain germacrene D at 4.72-6.18%.
- Observation These essential oils showed no antioxidant activity in vitro.
- Observation The oils were antimicrobial against Staphylococcus aureus with MIC 0.004 mg/mL.
- Observation The oils had MIC 0.03 mg/mL against Micrococcus luteus.
- Observation The oils had MMC 8.43 mg/mL against Micrococcus luteus.
- Observation The oils relaxed rat aorta with endothelium with EC50 305-544 μg/mL.
- Observation The oils relaxed rat aorta without endothelium with EC50 150-283 μg/mL.
- Observation The oils relaxed rat uterus with EC50 74-257 μg/mL.
- Observation The oils relaxed isolated guinea-pig trachea with minor potency.
- Recommendation Lippia thymoides is a source of natural products of pharmaceutical interest and further studies are needed to identify active substances.