Intervention effectmodel-written summary

Knocking down AaABC, AaAO and AaPDE decreased ALT7 pathogenicity.

A claim from AaAO, AaPDE, and AaABC proteins promote Alternaria alternate f. sp. mali ALT7 invasion in apple leaves · 2025

Intervention effectobservedoriginal resultpositivemeasured

Claim · model-written summary

Knocking down AaABC, AaAO and AaPDE decreased ALT7 pathogenicity.

Taxon: ALT7e0
Treatment: knocking them downe0
Outcome: pathogenicitye0
Direction: decreasede0

Not reportedMaterialGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleComparatorSettingValueQualifier

Verbatim

e0
“Conversely, knocking them down decreased ALT7 pathogenicity”
✓ located verbatim in the source · abstract, characters 992–1051

Title

AaAO, AaPDE, and AaABC proteins promote Alternaria alternate f. sp. mali ALT7 invasion in apple leaves

Jinqi Tang; Yan Li; Shun Gong; et al. Horticultural Plant Journal 2025. doi:10.1016/j.hpj.2024.08.008

Other claims from this paper (7)

Observation Eight novel ALT strains were isolated from Fuji apple leaves exhibiting leaf spot.
Observation The most aggressive strain, ALT7, was identified.
Observation LC-MS detected three ALT7 secreted proteins: AaAO, AaPDE and AaABC.
Observation Agrobacterium-mediated transgenesis confirmed the extracellular localization of GFP-fused AaAO, AaABC and AaPDE.
Intervention effect Overexpression of AaABC, AaAO and AaPDE in ALT7 increased its pathogenicity.
Mechanism AaABC facilitates the secretion of AaAO and AaPDE.
Mechanism AaAO and AaPDE facilitate plant susceptibility by degrading plant cell walls.

Record rev-942e3feb7a0a33aade11ab4d1e44759b56818b9b7cdd491023c6c441bdbb1be6 · schema claims-v0.9 · position 6 in the model’s answer