Claim · model-written summary
Knockdown and knockout mutants of eight pathogen genes remained virulent toward elm saplings.
- Taxon
- U. americana
Ulmus americanae0 - Treatment
- Knockdown- and knockout mutantse0
- Interactor
- O. novo-ulmiOphiostoma novo-ulmie0pathogen
- Outcome
- mutants remained virulent towards U. americana saplingse0
Not reportedMaterialGeneCompoundOrgan / stageSecond interactorSecond interactor roleComparatorSettingDirectionValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Knockdown- and knockout mutants were obtained for eight O. novo-ulmi genes. Although mutants remained virulent towards U. americana saplings”
Title
Martha Nigg; Thais C. de Oliveira; Jorge L. Sarmiento-Villamil; et al. Journal of Fungi 2022. doi:10.3390/jof8060637
Other claims from this paper (11)
- Observation Transcripts were identified for 6424 of 8640 annotated pathogen genes.
- Observation 1439 pathogen genes expressed in planta had PHI-base orthologs.
- Observation 472 pathogen genes were differentially expressed at 96 hpi.
- Observation 370 pathogen genes were differentially expressed in susceptible elms at 96 hpi.
- Observation 102 pathogen genes were differentially expressed in VF elms at 96 hpi.
- Observation Transport and transmembrane transport accounted for 27 of 55 enriched GO terms in genes upregulated in susceptible elms.
- Observation Nine of 22 enriched GO terms in genes overexpressed in VF elms involved carbohydrate metabolism, catabolism or transport.
- Association Three coexpression modules were significantly associated with higher pathogen gene expression in susceptible elms.
- Observation The three modules comprised 727 genes expressed in planta.
- Observation The three modules included 103 genes upregulated in susceptible elms.
- Observation The analysis identified additional candidate pathogen pathogenicity genes.