Claim · model-written summary
Eugenol suppresses glycolytic and tricarboxylic acid cycle enzyme activities.
- Taxon
- Hyphantria cunea
Hyphantria cuneat0 - Treatment
- eugenol treatmente0
- Gene
- hexokinase and nicotinamide adenine dinucleotide-isocitrate dehydrogenasee0
- Outcome
- activity of key rate-limiting enzymese0
- Direction
- suppressede0
Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleComparatorSettingValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Verbatim
e0“eugenol treatment suppressed the activity of key rate-limiting enzymes in the glycolytic pathway and tricarboxylic acid cycle (hexokinase and nicotinamide adenine dinucleotide-isocitrate dehydrogenase)”
t0“Hyphantria cunea”
Title
Yajun Wang; Jiangyan Xie; Yansheng Sun; et al. Journal of Economic Entomology 2026. doi:10.1093/jee/toag141
Other claims from this paper (14)
- Intervention effect Eugenol causes mortality and feeding deterrence in H. cunea larvae.
- Intervention effect Eugenol decreases larval food utilization efficiency.
- Intervention effect Eugenol significantly impairs larval digestion by inhibiting α-amylase, lipase and trypsin activities.
- Intervention effect Eugenol downregulates six digestive enzyme genes.
- Intervention effect Eugenol downregulates associated energy metabolism genes.
- Intervention effect Eugenol reduces Na+/K+-ATPase activity.
- Mechanism Eugenol's energy metabolism effects decrease ATP supply.
- Mechanism Eugenol's energy metabolism effects delay hydrolysis.
- Intervention effect Eugenol activates antioxidant enzymes.
- Intervention effect Eugenol upregulates antioxidant-related gene expression.
- Intervention effect Hydrogen peroxide and malondialdehyde contents increase despite antioxidant activation by eugenol.
- Intervention effect Eugenol impairs larval feeding on host plants.
- Observation Eugenol has low toxicity to non-target aquatic organisms.
- Recommendation Eugenol is recommended as a promising effective alternative for controlling invasive H. cunea.