Claim · model-written summary
AC5 reversed GFP transgene transcriptional silencing by reducing promoter methylation.
- Taxon
- Nicotiana benthamiana
Nicotiana benthamianae1 - Gene
- AC5e0
- Outcome
- transcriptional gene silencing of a green fluorescent protein transgenee0
- Direction
- reversee0
- Qualifier
- reducing methylation of promoter sequencese0
Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingValue
Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Verbatim
e0“AC5 was also able to reverse transcriptional gene silencing of a green fluorescent protein transgene by reducing methylation of promoter sequences”
t0“Mungbean yellow mosaic India virus”
e1“Ectopic expression of AC5 from a Potato virus X (PVX) vector resulted in severe mosaic symptoms followed by a hypersensitive-like response in Nicotiana benthamiana.”
Title
Fangfang Li; Xiongbiao Xu; Changjun Huang; et al. New Phytologist 2015. doi:10.1111/nph.13473
Other claims from this paper (6)
- Observation AC5 was critical for MYMIV infection.
- Intervention effect PVX vector expression of AC5 caused severe mosaic symptoms in Nicotiana benthamiana.
- Intervention effect PVX vector expression of AC5 induced a hypersensitive-like response.
- Observation MYMIV AC5 suppressed silencing induced by single-stranded RNA.
- Observation MYMIV AC5 did not suppress silencing induced by double-stranded RNA.
- Mechanism The proposed mechanism for AC5 silencing suppression includes repression of DOMAINS REARRANGED METHYLTRANSFERASE2.