Claim · model-written summary
Both roselle varieties showed antiproliferative activity against BxPC-3 pancreatic cancer cells with IC50 of 289.2-356.8 ug/mL.
- Taxon
- Hibiscus sabdariffa
Hibiscus sabdariffat0 - Outcome
- antiproliferative activity against BxPC-3 pancreatic cancer cellse0
- Value
- 289.2–356.8 μg/mLe0
Not reportedMaterialGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingDirectionQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Hibiscus sabdariffa”
e0“Both varieties exhibited antiproliferative activity against BxPC-3 pancreatic cancer cells (IC50: 289.2–356.8 μg/mL)”
Title
Yu-Hung Liao; Jing-Wen Chen; Yu-Chia Chang; et al. Foods 2026. doi:10.3390/foods15101696
Other claims from this paper (8)
- Observation The 50% EtOH leaf extracts of both roselle varieties were rich in neochlorogenic acid and cryptochlorogenic acid.
- Observation The 50% EtOH leaf extracts of both roselle varieties were rich in rutin and nicotiflorin.
- Observation Taitung No. 6 leaves uniquely contained higher levels of anthocyanins, including delphinidin-3-O-sambubioside and cyanidin-3-O-sambubioside.
- Intervention effect Acidified 50% EtOH extraction increased flavonoid aglycone and polyamine contents of roselle leaf extracts.
- Observation n-Hexane extracts of roselle leaves were identified as potential sources of vitamin E and alpha-linolenic acid.
- Observation n-Hexane extracts of roselle leaves were identified as potential sources of squalene and phytol.
- Observation Both roselle varieties significantly improved glucose uptake in insulin-resistant HepG2 cells.
- Mechanism Neochlorogenic acid and cryptochlorogenic acid were identified as the primary active contributors to the antiproliferative and glucose-uptake bioactivities.