Claim · model-written summary
Compounds identified in the essential oil presented low human and environmental toxicity in ADMETox predictions.
- Taxon
- Anemia tomentosa
Anemia tomentosae1 - Outcome
- human and environmental toxicitye6
- Qualifier
- lowe6
Not reportedMaterialGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingDirectionValue
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e1“The essential oil extracted from Anemia tomentosa (EOAT) has shown larvicidal potential against Aedes aegypti”
e6“Chemical compounds identified in the investigated essential oil presented low human and environmental toxicity, as observed in absorption, distribution, metabolism and excretion, and toxicity (ADMETox) predictions”
Title
Vilisaimon de Jesus; Juliana Leite; Jailan Sousa; et al. Journal of the Brazilian Chemical Society 2024. doi:10.21577/0103-5053.20240127
Other claims from this paper (7)
- Observation Sesquiterpenes made up 87.51% of the essential oil of Anemia tomentosa.
- Observation Presilphiperfolan-1-ol was the main component of the essential oil at 42.13%.
- Observation Silphiperfol-5-ene was present in the essential oil at 19.47%.
- Intervention effect Essential oil of Anemia tomentosa reached 100% mortality of Aedes aegypti larvae.
- Observation The essential oil showed potential cytotoxic activity up to 48 h of exposure in the larvicidal assay.
- Mechanism Compounds from Anemia tomentosa have potential to inhibit acetylcholinesterase in Aedes aegypti in silico.
- Association Triquinane sesquiterpene activity (-6.8 to -8.2 kcal mol-1) stood out compared with temephos (-7.5 kcal mol-1) in silico.