Claim · model-written summary
AVR3a associated with plant DRP2.
Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingDirectionValueQualifier
Verbatim
e0“AVR3a associates with the Dynamin-Related Protein 2 (DRP2), a plant GTPase implicated in receptor-mediated endocytosis.”
e1“in N. benthamiana using the elicitor/receptor pair flg22/FLS2 as a model.”
Title
Angela Chaparro-Garcia; Simon Schwizer; Jan Sklenar; et al. PLoS ONE 2015. doi:10.1371/journal.pone.0137071
Other claims from this paper (5)
- Intervention effect All tested AVR3a variants suppressed flg22-triggered defense responses in Nicotiana.
- Intervention effect All tested AVR3a variants reduced activated FLS2 internalization in Nicotiana.
- Intervention effect DRP2 silencing impaired ligand-induced FLS2 internalization.
- Intervention effect DRP2 silencing did not affect BRI1 internalization.
- Mechanism The authors interpret AVR3a as suppressing BAK1/SERK3-mediated immunity through at least two pathways.