Claim · model-written summary
The DNS extract inhibited butyrylcholinesterase with an IC50 of 52.55 +/- 0.72 ug/mL.
- Taxon
- Phoenix dactylifera
Phoenix dactyliferat0 - Material
- DNSe0
- Outcome
- butyrylcholinesterasee0
- Value
- IC 50 : 52.55 ± 0.72 µg/mLe0
Not reportedGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingDirectionQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“with the DNS extract exhibiting dual inhibitory activity against acetylcholinesterase (AChE, IC 50 : 3.17 ± 0.11 µg/mL) and butyrylcholinesterase (BChE, IC 50 : 52.55 ± 0.72 µg/mL)”
t0“Phoenix dactylifera”
Title
Maria Ferhat; Ahmed Kabouche; Zahia Kabouche; et al. Chemistry & Biodiversity 2026. doi:10.1002/cbdv.71404
Other claims from this paper (9)
- Observation Quinic acid was a major constituent of the Ghars variety extract from Ghardaia.
- Observation Ferulic acid predominated in the ethanolic extract of Deglat nour seeds.
- Observation Flavonoid glycosides such as rutin, isoquercetin and hesperidin were detected, with the highest levels in DNS.
- Observation DNS and GG were the most antibacterial extracts, the other fractions moderate to weak.
- Association The strongest effects matched higher phenolic and flavonoid levels (catechin, quinic acid, isoquercetin), which the authors suggest drive the activity.
- Observation The DNS extract inhibited acetylcholinesterase with an IC50 of 3.17 +/- 0.11 ug/mL.
- Observation DNS AChE inhibitory activity was stronger than that of the reference standard galantamine (IC50 5.01 +/- 0.11 ug/mL).
- Observation DNS BChE inhibition was comparable to the standard (IC50 53.90 +/- 0.56 ug/mL).
- Observation The Deglat nour spikelet extract showed selective BChE inhibition (IC50 43.28 +/- 0.83 ug/mL), more potent than galantamine.