Claim · model-written summary
AtMYB48 and AtbHLH68 function as negative regulators of xylem differentiation.
- Taxon
- Arabidopsis
Arabidopsist0 - Gene
- AtMYB48 and AtbHLH68e0
- Outcome
- xylem differentiatione0
- Direction
- negative regulatorse0
Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Arabidopsis thaliana”
e0“Both AtMYB48 and AtbHLH68 are direct targets of AtMYB2 and function as positive regulators of cambial cell proliferation and negative regulators of xylem differentiation”
Title
Chong Zhang; Xiaorui Guo; Leiqian Sun; et al. Plant Communications 2026. doi:10.1016/j.xplc.2026.101939
Other claims from this paper (13)
- Intervention effect Overexpression of AtMYB2 decreases cambial cell numbers.
- Intervention effect Overexpression of AtMYB2 increases xylem cell numbers.
- Intervention effect Loss of AtMYB2 results in the opposite phenotype to overexpression.
- Mechanism The authors conclude that AtMYB2 negatively regulates cambial cell proliferation.
- Mechanism The authors conclude that AtMYB2 positively regulates xylem cell differentiation.
- Observation AtMYB48 and AtbHLH68 are direct targets of AtMYB2.
- Mechanism AtMYB48 and AtbHLH68 function as positive regulators of cambial cell proliferation.
- Observation Single mutants of AtMYB48 or AtbHLH68 exhibit only mild phenotypic alterations.
- Observation The atmyb48 atbhlh68 double mutant displays enhanced defects in xylem development.
- Intervention effect Overexpression of either AtMYB48 or AtbHLH68 alone rescues the double mutant phenotype, indicating functional redundancy.
- Observation AtMYB48 and AtbHLH68 can physically interact, but this interaction is dispensable for their regulatory functions in xylem development.
- Observation AtMYB48 primarily regulates genes associated with secondary cell wall deposition and programmed cell death.
- Observation AtbHLH68 predominantly regulates genes involved in cambial cell proliferation.