Intervention effectmodel-written summary

Constitutive expression of BIN2 attenuated plant resistance to Verticillium dahliae.

A claim from BIN2 negatively regulates plant defence against Verticillium dahliae in Arabidopsis and cotton · 2021

Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

Constitutive expression of BIN2 attenuated plant resistance to Verticillium dahliae.

Taxon
Arabidopsis and cottonGossypium hirsutumArabidopsise1
Treatment
Constitutive expression of BIN2e2
Interactor
V. dahliaeVerticillium dahliaee2pathogen
Gene
BIN2e2
Outcome
plant resistancee2
Direction
attenuatede2

Not reportedMaterialCompoundOrgan / stageSecond interactorSecond interactor roleComparatorSettingValueQualifier

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Gossypium hirsutum
Gossypium hirsutum · TaxonChriKo · CC BY-SA 3.0 · Wikimedia Commons ↗
Arabidopsis
Arabidopsis · Taxon · picture of the genus (one of its species)Original uploader was Brona at en.wikipedia . User:Roepers at nl.wikipedia · CC BY-SA 3.0 · Wikimedia Commons ↗
Verticillium dahliae
Verticillium dahliae · InteractorHoward F. Schwartz · CC BY 3.0 us · Wikimedia Commons ↗

Verbatim

e1

“The Verticillium wilt resistance of Arabidopsis and cotton were significantly enhanced when BIN2 was knocked down”

✓ located verbatim in the source · abstract, characters 572–685
e2

“Constitutive expression of BIN2 attenuated plant resistance to V. dahliae”

✓ located verbatim in the source · abstract, characters 687–760

Title

BIN2 negatively regulates plant defence against Verticillium dahliae in Arabidopsis and cotton

Yun Song; Yaohua Zhai; Linxuan Li; et al. Plant Biotechnology Journal 2021. doi:10.1111/pbi.13640

Other claims from this paper (6)

Record rev-d5fb4e5ba914293ca41c36ea87d29053e72ec502b557db75d78cdec6af37959c · schema claims-v0.9 · position 2 in the model’s answer

overexpression · Verticillium dahliae · Gossypium hirsutum (cotton)Positive and negative results

5 papers: 2 positive, 3 negative or no effect

2 papers in the same direction as this claim · 2 in the opposite direction

  1. positive
    Ectopic GhPMEI3 expression limited fungal disease in cotton.

    A Pectin Methylesterase Inhibitor Enhances Resistance to Verticillium Wilt · 2018

    Opposite direction

  2. positive
    Ectopic GhPMEI3 expression limited fungal disease in cotton.

    柳田国男の「一国民俗学」誕生に関する一考察 : ハインリッヒ・ハイネ著「流謫の神々」の思想的な影響 · 2003

    Opposite direction

  3. negative
    Vd6317 expression enhanced cotton susceptibility to V. dahliae.

    Suppression of plant immunity by Verticillium dahliae effector Vd6317 through AtNAC53 association · 2024

    Same direction

  4. negative
    Ectopic expression of Vd06254 enhanced susceptibility of cotton to V. dahliae infection.

    Verticillium dahliae effector Vd06254 disrupts cotton defence response by interfering with GhMYC3‐GhCCD8‐mediated hormonal crosstalk between jasmonic acid and strigolactones · 2025

    Same direction

See all 5 papers →

overexpression · Verticillium dahliae · ArabidopsisResults agree

3 papers: 0 positive, 3 negative or no effect

2 papers in the same direction as this claim

  1. negative
    Ectopic GausACLB-2 expression weakened Arabidopsis resistance to V. dahliae in Col-0.

    ATP-citrate lyase B (ACLB) negatively affects cell death and resistance to Verticillium wilt · 2022

    Same direction

  2. negative
    Vd6317 expression enhanced Arabidopsis susceptibility to V. dahliae.

    Suppression of plant immunity by Verticillium dahliae effector Vd6317 through AtNAC53 association · 2024

    Same direction

See all 3 papers →

Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.

Functional evidence on BIN2

Claims that state a gain or loss of function of this gene and what it did to a trait, compared with wild type or a control.

BIN2 · Open in the knowledge graph

Gossypium hirsutum (cotton)1 paper · 1 traitTested in one paper only

Only one paper in the store tests this gene's function in Gossypium hirsutum (cotton).

Disease resistance1 paper

  1. Restrains
    Constitutive expression of BIN2 attenuated plant resistance to Verticillium dahliae.

    BIN2 negatively regulates plant defence against Verticillium dahliae in Arabidopsis and cotton · 2021

    gain of function → less of the traitThis claim

The program reads each claim's manipulation and the direction of the trait, and from them the gene's role (gain and more, or loss and less, means it promotes the trait). Roles are read by program from each claim's wording. Pairs of papers on the same host, gene and trait were checked claim by claim by two model readers; a pair is marked checked only when both accept it. Gene layer v0.8, 21 trait classes.