Claim · model-written summary
Minimum inhibitory concentrations ranged between 62.5 and 500 µg/mL against the ESKAPE isolates.
- Taxon
- Newbouldia laevis
Newbouldia laevist0 - Interactor
- ESKAPE isolatese5pathogen
- Outcome
- MIC valuese7
- Value
- 62.5 and 500 µg/mLe7
Not reportedMaterialGeneCompoundOrgan / stageSecond interactorSecond interactor roleTreatmentComparatorSettingDirectionQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
t0“Newbouldia laevis Root Methanol Extract against ESKAPE Pathogens”
e5“The methanol extract demonstrated significant antibacterial activity against all ESKAPE isolates”
e7“MIC values between 62.5 and 500 µg/mL”
Title
Ikemesit Udeme Peter; Ugonna Cassandra Aniokete; Ijeoma Onyinye Okolo; et al. Asian Plant Research Journal 2026. doi:10.9734/aprj/2026/v14i2370
Other claims from this paper (10)
- Observation GC-MS of the root methanol extract detected 24 bioactive compounds.
- Observation Gamma-sitosterol was the major constituent of the root extract, at 24.50%.
- Observation Stigmasterol was a major constituent of the root extract, at 12.30%.
- Observation Betulinic acid was a major constituent of the root extract, at 8.20%.
- Observation Ursolic acid was a major constituent of the root extract, at 6.80%.
- Observation The root methanol extract had significant antibacterial activity against all ESKAPE isolates tested.
- Observation Zones of inhibition ranged from 12.3 ± 1.2 mm to 28.6 ± 1.8 mm against the ESKAPE isolates.
- Observation S. aureus was the most susceptible isolate, with an MIC of 62.5 µg/mL.
- Observation E. faecium showed relative resistance to the root extract, with an MIC of 500 µg/mL.
- Recommendation The authors propose the root extract as a source of lead compounds for new antimicrobial agents.