Claim · model-written summary
Efflux transporters mediated cross-resistance across fungicide classes.
- Taxon
- wheat
Triticum aestivume1 - Interactor
- Pyrenophora tritici-repentis
Pyrenophora tritici-repentise1pathogen - Gene
- Efflux transporterse0
- Outcome
- cross-resistance to a number of fungicidese0
Not reportedMaterialCompoundOrgan / stageSecond interactorSecond interactor roleTreatmentComparatorSettingDirectionValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Efflux transporters can mediate cross-resistance to a number of fungicides that belong to different chemical classes and have different modes of action”
e1“wheat tan spot, Pyrenophora tritici-repentis”
Title
Sven Reimann; Holger B. Deising Applied and Environmental Microbiology 2005. doi:10.1128/aem.71.6.3269-3275.2005
Other claims from this paper (7)
- Observation Field isolates of the wheat tan spot pathogen had reduced sensitivity to strobilurin and azole fungicides.
- Observation Efflux transporter activity was inducible under field conditions and sublethal fungicide application.
- Observation Resistant isolates grew on fungicide-amended substrata.
- Observation Resistant isolates infected plants despite above-recommended fungicide treatment.
- Observation 2-(4-ethoxy-phenyl)-chromen-4-one inhibited energy-dependent fungicide efflux transporters.
- Intervention effect Combining the inhibitor with fungicides restored resistant isolates to normal sensitivity.
- Intervention effect Combining the inhibitor with fungicides prevented wheat leaf infection.