Claim · model-written summary
E2F element mutation increased transcription in healthy mature leaves.
- Taxon
- Nicotiana benthamiana
Nicotiana benthamianae7 - Organ / stage
- healthy mature leavese0
- Treatment
- Mutation of an E2F consensus elemente1
- Outcome
- transcriptione0
- Direction
- increasede0
Not reportedMaterialGeneCompoundInteractorInteractor roleSecond interactorSecond interactor roleComparatorSettingValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“increased transcription in healthy mature leaves”
e7“mature cells of Nicotiana benthamiana”
e1“Mutation of an E2F consensus element in the PCNA promoter had no effect on its activity in young leaves”
Title
Erin M. Egelkrout; Dominique Robertson; Linda Hanley-Bowdoin The Plant Cell 2001. doi:10.1105/tpc.010004
Other claims from this paper (8)
- Observation A PCNA transcript was detected in young leaves.
- Intervention effect PCNA RNA occurred in infected mature leaves but not healthy mature leaves.
- Observation The PCNA promoter supported high expression in cultured cells and young healthy leaves, but not mature healthy leaves.
- Intervention effect TGMV infection yielded PCNA promoter activity in both young and mature leaves.
- Association Symptom severity, viral DNA, PCNA promoter activity and PCNA mRNA were strongly related.
- Intervention effect E2F element mutation did not change PCNA promoter activity in young leaves.
- Intervention effect TGMV infection had no detectable effect on mutant E2F promoter activity.
- Mechanism The authors infer that geminivirus induces a host replication factor by activating transcription, probably overcoming E2F repression.