Intervention effectmodel-written summary

WRKY8 silencing decreased defense gene expression.

A claim from Phosphorylation of the Nicotiana benthamiana WRKY8 Transcription Factor by MAPK Functions in the Defense Response   · 2011

Intervention effectobservedoriginal resultnegativemeasured

Claim · model-written summary

WRKY8 silencing decreased defense gene expression.

Taxon
Nicotiana benthamianaNicotiana benthamianat0
Treatment
silencing of WRKY8e0
Outcome
expression of defense-related genese0
Direction
decreasede0

Not reportedMaterialGeneCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleComparatorSettingValueQualifier

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Nicotiana benthamiana
Nicotiana benthamiana · TaxonCharles Andres · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“silencing of WRKY8 decreased the expression of defense-related genes”

✓ located verbatim in the source · abstract, characters 1124–1192
t0

“Nicotiana benthamiana”

✓ located verbatim in the source · title, characters 23–44

Title

Phosphorylation of the Nicotiana benthamiana WRKY8 Transcription Factor by MAPK Functions in the Defense Response  

Nobuaki Ishihama; Reiko Yamada; Miki Yoshioka; et al. The Plant Cell 2011. doi:10.1105/tpc.110.081794

Other claims from this paper (9)

Record rev-bf5bcb97848a37d5d52d95bd19b0e6131f01aa3519328cad80381720c53027b0 · schema claims-v0.9 · position 8 in the model’s answer

loss of function · molecular: expression · Nicotiana benthamianaPositive and negative results

43 papers: 19 positive, 24 negative or no effect

23 papers in the same direction as this claim · 19 in the opposite direction

  1. negative
    Silencing multiple WRKY genes compromised RBOHB upregulation.

    WRKY Transcription Factors Phosphorylated by MAPK Regulate a Plant Immune NADPH Oxidase in Nicotiana benthamiana · 2015

    Same directionCites this paper

  2. positive
    GAPC silencing enhanced N gene-mediated cell death.

    Cytoplastic Glyceraldehyde-3-Phosphate Dehydrogenases Interact with ATG3 to Negatively Regulate Autophagy and Immunity in Nicotiana benthamiana · 2015

    Opposite direction

  3. positive
    E2F element mutation increased PCNA transcription in healthy mature leaves.

    Proliferating Cell Nuclear Antigen Transcription Is Repressed through an E2F Consensus Element and Activated by Geminivirus Infection in Mature Leaves · 2001

    Opposite direction

  4. positive
    Deleting 22 C-terminal amino acids increased L1 expression yield fourfold.

    Comparative analysis of recombinant Human Papillomavirus 8 L1 production in plants by a variety of expression systems and purification methods · 2012

    Opposite direction

  5. positive
    Silencing the MKK2 homolog reduced XopAU cell death and MAPK phosphorylation in N. benthamiana.

    The Xanthomonas euvesicatoria type III effector XopAU is an active protein kinase that manipulates plant MAP kinase signaling · 2018

    Opposite direction

  6. positive
    The TBSV P19 protein prolonged expression until 7 dpi.

    Development of a Reverse Genetic System for Studying Rose Rosette Virus in Whole Plants · 2020

    Opposite direction

  7. positive
    NbAGO2 participated in RNA interference, as silencing restored GFP expression.

    miR403a and SA Are Involved in NbAGO2 Mediated Antiviral Defenses Against TMV Infection in Nicotiana benthamiana · 2019

    Opposite direction

  8. positive
    E2F element mutation increased transcription in healthy mature leaves.

    Proliferating Cell Nuclear Antigen Transcription Is Repressed through an E2F Consensus Element and Activated by Geminivirus Infection in Mature Leaves · 2001

    Opposite direction

34 papers more in this group

See all 43 papers →

Claims are grouped by organism, treatment and what was measured or targeted. A paper counts as positive when any of its claims in the group is positive.