Claim · model-written summary
NLP7 directly downregulates the expression of WRKY18
- Taxon
- Arabidopsis thaliana
Arabidopsis thalianae0 - Gene
- WRKY18e4
- Outcome
- expression of TFse4
- Direction
- downregulatee4
Not reportedMaterialCompoundOrgan / stageInteractorInteractor roleSecond interactorSecond interactor roleTreatmentComparatorSettingValueQualifier
Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Verbatim
e0“Through a comprehensive transcriptomic meta-analysis in Arabidopsis thaliana”
e4“NLP7 directly downregulate the expression of TFs such as HB6 , NAC6 , NAP , and WRKY18”
Title
Nathan R. Johnson; Tomás C. Moyano; Viviana Araus; et al. Proceedings of the National Academy of Sciences 2026. doi:10.1073/pnas.2509904122
Other claims from this paper (9)
- Observation NLP7 accounts for 85% of the transcriptional interaction between nitrogen and water deficit pathways in Arabidopsis thaliana
- Observation Nitrogen supply and water deficit signaling show overlapping and often opposing gene expression responses in Arabidopsis thaliana
- Observation NLP7 is identified by regulatory network modeling as a central integrator of convergent transcriptional responses
- Association NLP7 directly downregulates the expression of HB6, NAC6 and NAP
- Observation Repression of secondary TFs by NLP7 has distinct downstream effects on gene expression
- Intervention effect Loss of NLP7 enhances water deficit tolerance relative to wild-type plants
- Intervention effect Loss of NLP7 increases water retention relative to wild-type plants
- Intervention effect Loss of NLP7 reduces ABA-mediated stomatal aperture relative to wild-type plants
- Observation Loss of NLP7 alters expression of stress-responsive genes under water deficit