Paper · 1980 · Planta Medica

Phototoxicity in Heracleum sphondylium

G. Weimarck; E. Nilsson

7
claims
14
verbatim quotes
27
citations
2
research areas
—
Not open access

Abstract

Phototoxicity of leaf extracts of nine subspecies of Heracleum sphondylium lat. was tested using Candida albicans is a test organism and the results were roughly quantified. The leaves of the subspecies sphondylium and sibircum were usually non-phototoxic. Variation was observed within the subspecies granatense and ternatum. The subspecies alpinum, transsilvanicum, pyre-naicum, montanum and orsinii were moderately to strongly phototoxic. Morphologically variable populations varied correspondingly in the degree of phototoxicity. Fruits were phototoxic in all taxa studied and roots in all taxa but subsp. alpinum. Evidence from thin-layer chromatography suggests that phototoxicity may be caused by the 6,7-furocoumarins (psoralens) xanthotoxin, bergapten, imperatorin and a non-identified compound. Ecological effects and taxonomical implications are briefly discussed. Key Word Index Heracleum sphondylium - Apiaceae (Umbelliferae) - Phototoxicity - Furocoumarins - Candida Test.

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Claims 7

Observationobservedoriginal resultno effectmeasured

Claim · model-written summary

Leaves of subspecies sphondylium and sibircum were usually non-phototoxic.

Taxon
Heracleum sphondyliumHeracleum sphondyliumt0
Material
subspecies sphondylium and sibircume0
Organ / stage
leavese0
Outcome
non-phototoxice0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Heracleum sphondylium
Heracleum sphondylium · TaxonChristian Fischer · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“The leaves of the subspecies sphondylium and sibircum were usually non-phototoxic.”

✓ located verbatim in the source · abstract, characters 174–256 · show in text ↑
t0

“Heracleum sphondylium”

✓ located verbatim in the source · title, characters 17–38 · show in text ↑
Observationobservedoriginal resultmixedmeasured

Claim · model-written summary

Phototoxicity varied within subspecies granatense and ternatum.

Taxon
Heracleum sphondyliumHeracleum sphondyliumt0
Material
subspecies granatense and ternatume0
Outcome
Variatione0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Heracleum sphondylium
Heracleum sphondylium · TaxonChristian Fischer · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“Variation was observed within the subspecies granatense and ternatum.”

✓ located verbatim in the source · abstract, characters 257–326 · show in text ↑
t0

“Heracleum sphondylium”

✓ located verbatim in the source · title, characters 17–38 · show in text ↑
Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

Five named subspecies were moderately to strongly phototoxic.

Taxon
Heracleum sphondyliumHeracleum sphondyliumt0
Material
subspecies alpinum, transsilvanicum, pyre-naicum, montanum and orsiniie0
Outcome
phototoxice0
Qualifier
moderately to stronglye0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Heracleum sphondylium
Heracleum sphondylium · TaxonChristian Fischer · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“The subspecies alpinum, transsilvanicum, pyre-naicum, montanum and orsinii were moderately to strongly phototoxic.”

✓ located verbatim in the source · abstract, characters 327–441 · show in text ↑
t0

“Heracleum sphondylium”

✓ located verbatim in the source · title, characters 17–38 · show in text ↑
Associationobservedoriginal resultmixedmeasured

Claim · model-written summary

Morphologically variable populations also varied in degree of phototoxicity.

Taxon
Heracleum sphondyliumHeracleum sphondyliumt0
Material
Morphologically variable populationse0
Outcome
degree of phototoxicitye0

Not reportedDirection

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Heracleum sphondylium
Heracleum sphondylium · TaxonChristian Fischer · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“Morphologically variable populations varied correspondingly in the degree of phototoxicity.”

✓ located verbatim in the source · abstract, characters 442–533 · show in text ↑
t0

“Heracleum sphondylium”

✓ located verbatim in the source · title, characters 17–38 · show in text ↑
Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

Fruits were phototoxic in every taxon studied.

Taxon
Heracleum sphondyliumHeracleum sphondyliumt0
Organ / stage
Fruitse0
Outcome
phototoxice0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Heracleum sphondylium
Heracleum sphondylium · TaxonChristian Fischer · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“Fruits were phototoxic in all taxa studied”

✓ located verbatim in the source · abstract, characters 534–576 · show in text ↑
t0

“Heracleum sphondylium”

✓ located verbatim in the source · title, characters 17–38 · show in text ↑
Observationobservedoriginal resultpositivemeasured

Claim · model-written summary

Roots were phototoxic in all taxa except subsp. alpinum.

Taxon
Heracleum sphondyliumHeracleum sphondyliumt0
Organ / stage
rootse0
Outcome
roots in all taxa but subsp. alpinume0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Heracleum sphondylium
Heracleum sphondylium · TaxonChristian Fischer · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“roots in all taxa but subsp. alpinum”

✓ located verbatim in the source · abstract, characters 581–617 · show in text ↑
t0

“Heracleum sphondylium”

✓ located verbatim in the source · title, characters 17–38 · show in text ↑
Mechanismhypothesisoriginal resultmeasured

Claim · model-written summary

Chromatography suggested that four furocoumarins may cause phototoxicity.

Taxon
Heracleum sphondyliumHeracleum sphondyliumt0
Compound
6,7-furocoumarins (psoralens)e0
Outcome
phototoxicitye0
Qualifier
may be causede0

Organisms pictured · Representative pictures of the matched species, not figures from the paper.

Heracleum sphondylium
Heracleum sphondylium · TaxonChristian Fischer · CC BY-SA 3.0 · Wikimedia Commons ↗

Verbatim

e0

“phototoxicity may be caused by the 6,7-furocoumarins (psoralens) xanthotoxin, bergapten, imperatorin and a non-identified compound”

✓ located verbatim in the source · abstract, characters 673–803 · show in text ↑
t0

“Heracleum sphondylium”

✓ located verbatim in the source · title, characters 17–38 · show in text ↑