Abstract
In many interactions of plants with pathogens, the primary host defense reaction is accompanied by plant cell death at the site of infection. The resulting lesions are correlated with the establishment of an inducible resistance in plants called systemic acquired resistance (SAR), for which salicylic acid (SA) accumulation is a critical signaling event in Arabidopsis and tobacco. In Arabidopsis, the lesions simulating disease (lsd) mutants spontaneously develop lesions in the absence of pathogen infection. Furthermore, lsd mutants express SAR marker genes when lesions are present and are resistant to the same spectrum of pathogens as plants activated for SAR by necrogenic pathogen infection. To assess the epistatic relationship between SA accumulation and cell death, transgenic Arabidopsis unable to accumulate SA due to the expression of the salicylate hydroxylase (nahG) gene were used in crosses with the dominant mutants lsd2 or lsd4. Progeny from the crosses were inhibited for SAR gene expression and disease resistance. However, these progeny retained the spontaneous cell death phenotype similar to siblings not expressing nahG. Because lesions form in the absence of SA accumulation for isd2 and lsd4, a model is suggested in which lesion formation in these two mutants is determined prior to SA accumulation in SAR signal transduction. By contrast, the loss of SAR gene expression and disease resistance in nahG-expressing lsd mutants indicates that these traits are dependent upon SA accumulation in the SAR signal transduction pathway.
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Claims 5
Claim · model-written summary
nahG-expressing lsd2 or lsd4 progeny were inhibited for SAR gene expression.
- Taxon
- Arabidopsis
Arabidopsise1 - Treatment
- expression of the salicylate hydroxylase (nahG) genee1
- Outcome
- SAR gene expressione0
- Direction
- inhibitede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Progeny from the crosses were inhibited for SAR gene expression and disease resistance.”
e1“transgenic Arabidopsis unable to accumulate SA due to the expression of the salicylate hydroxylase (nahG) gene were used in crosses with the dominant mutants lsd2 or lsd4.”
Claim · model-written summary
nahG-expressing lsd2 or lsd4 progeny were inhibited for disease resistance.
- Taxon
- ArabidopsisArabidopsise1
- Treatment
- expression of the salicylate hydroxylase (nahG) genee1
- Outcome
- disease resistancee0
- Direction
- inhibitede0
Not reportedComparator
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“Progeny from the crosses were inhibited for SAR gene expression and disease resistance.”
e1“transgenic Arabidopsis unable to accumulate SA due to the expression of the salicylate hydroxylase (nahG) gene were used in crosses with the dominant mutants lsd2 or lsd4.”
Claim · model-written summary
The same progeny retained spontaneous cell death similar to siblings without nahG.
- Taxon
- ArabidopsisArabidopsise1
- Treatment
- expression of the salicylate hydroxylase (nahG) genee1
- Outcome
- spontaneous cell death phenotypee0
- Direction
- similare0
- Comparator
- siblings not expressing nahGe0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“these progeny retained the spontaneous cell death phenotype similar to siblings not expressing nahG.”
e1“transgenic Arabidopsis unable to accumulate SA due to the expression of the salicylate hydroxylase (nahG) gene”
Claim · model-written summary
The authors suggest lesion formation precedes salicylic acid accumulation in SAR signaling.
- Taxon
- ArabidopsisArabidopsist0
- Outcome
- lesion formatione0
- Qualifier
- prior to SA accumulation in SAR signal transductione0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“lesion formation in these two mutants is determined prior to SA accumulation in SAR signal transduction.”
t0“Arabidopsis”
Claim · model-written summary
SAR gene expression and disease resistance in lsd mutants depend on salicylic acid accumulation.
- Taxon
- ArabidopsisArabidopsist0
- Outcome
- SAR gene expression and disease resistancee0
- Qualifier
- dependent upon SA accumulatione0
Organisms pictured · Representative pictures of the matched species, not figures from the paper.
Verbatim
e0“SAR gene expression and disease resistance in nahG-expressing lsd mutants indicates that these traits are dependent upon SA accumulation in the SAR signal transduction pathway.”
t0“Arabidopsis”
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